Pharmacokinetics of oxytetracycline in the turkey: evaluation of biliary and urinary excretion
1989
Dyer, D.C.
Oxytetracycline (OTC) pharmacokinetic values in plasma and bile were ascertained after IV administration of the drug. At 6 hours after administration of 1 mg of OTC/kg of body weight, 2.15% of the dose was found in the bile and 37.6% was found in the urine. At 2 hours after administration, the peak bile-to-plasma OTC concentration ratio was 60:1. Bioavailability of OTC was 47.6% when it was administered orally to fasted turkeys and was 9.4% when administered to fed turkeys.
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书目信息
出版者
Multidisciplinary Digital Publishing Institute
其它主题
Male; Biological availability
语言
英语
类型
Journal Article; Text
2024-02-29
2026-02-03
MODS