Impact of Fenugreek on Milk Production in Rodent Models of Lactation Challenge
2019
Sevrin, Thomas | Alexandre-Gouabau, Marie Cécile | Castellano, Blandine | Aguesse, Audrey | Ouguerram, Khadija | Ngyuen, Patrick | Darmaun, Dominique | Boquien, Clair-Yves | Physiopathologie des Adaptations Nutritionnelles (PhAN) ; Institut National de la Recherche Agronomique (INRA)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE) ; Université de Nantes (UN)-Université de Nantes (UN)
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显示更多 [+] 显示较少 [-]英语. dietary supplementation of fenugreek, compared to control dams fed 20% protein diet with eight pups' litters. Milk flow was measured by the deuterium oxide enrichment method, and milk composition was assessed. Lipid and glucose metabolism parameters were assessed in dam and offspring plasmas. Fenugreek increased milk production by 16% in the litter size increase challenge, resulting in an 11% increase in pup growth without deleterious effect on dam-litter metabolism. Fenugreek had no effect in the maternal protein restriction challenge. These results suggest a galactologue effect of fenugreek when mothers have no physiological difficulties in producing milk.
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