Matrine and icariin can inhibit bovine viral diarrhoea virus replication by promoting type I interferon response in vitro

Cai Dongjie; Shen Zifan; Tian Bin; Chen Jie; Zhang Yilin; Shen Liuhong; Wang Ya; Ma Xiaoping; Zuo Zhicai

Matrine and icariin can inhibit bovine viral diarrhoea virus replication by promoting type I interferon response in vitro

2024

Bovine viral diarrhoea virus (BVDV) can cause diarrhoea (BVD) in an animal herd, leading to heavy economic losses. There are limited drugs available for treating and controlling BVD. This research aims to investigate the antiviral and immunoregulatory effects of two traditional Chinese herb extracts against BVDV infection. The extracts are matrine and icariin, which have been proved to have immunostimulant and antiviral effects.

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