Aphylogenetic study on the NP gene of detected canine distemper virus in (2008-2011) Iran
2014
Namroodi, Somayeh | Rostami, Amir | Majidzadeh Ardebili, Keivan | Ghalyanchi Langroudi, Arash
BACKGROUND: Canine Distemper (CD) is a lethal systemicdisease affecting a wide variety of terrestrial carnivores.OBJECTIVES: This study was performed to survey epidemiologicaland molecular characteristics of the canine distemper virus(CDV) strains circulating in Iran. METHODS: In this study, 19CDV-suspected unvaccinated dogs from Northeast and center ofIran were analyzed for presence of CDV nucleoprotein (NP) geneusing Nested-PCR during 2008- 2011. Different biological samplesof 14 dogs were positive. RESULTS: The phylogenetic analysisbased on partial NP gene sequences indicated the presence of twomajor clusters that are clearly different from vaccine strains in Iran.One cluster belongs to the European group and the other one to theArctic group. CONCLUTIONS: Due to a lack of phylogeneticanalysis on CDV in countries bordering Iran, except Turkey, theancestor of Iranian sequences specially Iranian Arctic sequencescould not be definitely identified. This study is the first report onphylogenetic analysis of CDV from domestic dogs in Iran.
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