Agro-Environmental Determinants of Leptospirosis: A Retrospective Spatiotemporal Analysis (2004–2014) in Mahasarakham Province (Thailand)
2021
Viroj, Jaruwan | Claude, Julien | Lajaunie, Claire | Cappelle, Julien | Kritiyakan, Anamika | Thuainan, Pornsit | Chewnarupai, Worachead | Morand, Serge | Institut des Sciences de l'Evolution de Montpellier (UMR ISEM) ; Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École Pratique des Hautes Études (EPHE) ; Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Université de Montpellier (UM)-Institut de recherche pour le développement [IRD] : UR226-Centre National de la Recherche Scientifique (CNRS) | Laboratoire Population-Environnement-Développement (LPED) ; Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU) | Animal, Santé, Territoires, Risques et Ecosystèmes (UMR ASTRE) ; Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Département Systèmes Biologiques (Cirad-BIOS) ; Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad) | Kasetsart University [Bangkok, Thailand] (KU) | Mahasarakham University | Ban Ke Health Promotion Hospital | This research was funded by the French ANR (project FutureHealthSEA "Predictive scenarios of health in Southeast Asia"), grant number ANR-17-CE35-0003-01, S.M. is supported by the Thailand International Cooperation Agency (TICA) "Animal Innovative Health" | ANR-17-CE35-0003,FutureHealthSEA,Scénarios de la santé en Asie du Sud-Est: changements d'utilisation des terres, changement climatique et maladies infectieuses(2017)
International audience
显示更多 [+] 显示较少 [-]英语. Leptospirosis has been recognized as a major public health concern in Thailand following dramatic outbreaks. We analyzed human leptospirosis incidence between 2004 and 2014 in Mahasarakham province, Northeastern Thailand, in order to identify the agronomical and environmental factors likely to explain incidence at the level of 133 sub-districts and 1982 villages of the province. We performed general additive modeling (GAM) in order to take the spatial-temporal epidemiological dynamics into account. The results of GAM analyses showed that the average slope, population size, pig density, cow density and flood cover were significantly associated with leptospirosis occurrence in a district. Our results stress the importance of livestock favoring leptospirosis transmission to humans and suggest that prevention and control of leptospirosis need strong intersectoral collaboration between the public health, the livestock department and local communities. More specifically, such collaboration should integrate leptospirosis surveillance in both public and animal health for a better control of diseases in livestock while promoting public health prevention as encouraged by the One Health approach.
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