Prediction Tool to Estimate Potassium Diet in Chronic Kidney Disease Patients Developed Using a Machine Learning Tool: The UniverSel Study
2022
Granal, M. | Slimani, L. | Florens, N. | Sens, F. | Pelletier, C. | Pszczolinski, R. | Casiez, C. | Kalbacher, E. | Jolivot, A. | Dubourg, L. | Lemoine, S. | Pasian, C. | Ducher, M. | Fauvel, J. P. | Hôpital Edouard Herriot [CHU - HCL] ; Hospices Civils de Lyon (HCL) | Université Claude Bernard Lyon 1 (UCBL) ; Université de Lyon | Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN) ; Université Claude Bernard Lyon 1 (UCBL) ; Université de Lyon-Université de Lyon-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Ciblage thérapeutique en Oncologie (EA3738) ; Université Claude Bernard Lyon 1 (UCBL) ; Université de Lyon-Université de Lyon
International audience
显示更多 [+] 显示较少 [-]英语. There is a need for a reliable and validated method to estimate dietary potassium intake in chronic kidney disease (CKD) patients to improve prevention of cardiovascular complications. This study aimed to develop a clinical tool to estimate potassium intake using 24-h urinary potassium excretion as a surrogate of dietary potassium intake in this high-risk population. Data of 375 adult CKD-patients routinely collecting their 24-h urine were included to develop a prediction tool to estimate potassium diet. The prediction tool was built from a random sample of 80% of patients and validated on the remaining 20%. The accuracy of the prediction tool to classify potassium diet in the three classes of potassium excretion was 74%. Surprisingly, the variables related to potassium consumption were more related to clinical characteristics and renal pathology than to the potassium content of the ingested food. Artificial intelligence allowed to develop an easy-to-use tool for estimating patients' diets in clinical practice. After external validation, this tool could be extended to all CKD-patients for a better clinical and therapeutic management for the prevention of cardiovascular complications.
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