Beneficial Properties of Trametes Versicolor Heteropolysaccharides in a Rat Model of Metabolic Syndrome
2024
Stojanović, Aleksandra | Nikolić, Marina | Lazarević, Nevena | Novaković, Jovana | Jeremić, Nevena | Živković, Vladimir | Bradić, Jovana | Jakovljević, Vladimir
We aimed to examine the potentially beneficial effects of Trametes versicolor heteropolysaccharides (TVH) on redox balance in a rats with metabolic syndrome (MetS). Total of 40 Wistar rats were divided into 5 groups: CTRL healthy non-treated rats; MetS-non-treated rats; H-TV (high dose of TV), M-TV (medium dose of TV) and L-TV (low dose of TV)-rats with MetS treated with either 300, 200 or 100 mg/kg TVH per os for 4 weeks. Prooxidative parameters and parameters of the antioxidative defense system were determined spectrophotometrically. H-TV and M-TV significantly reduced the level of prooxidants and increased antioxidants activity. The obtained results demonstrated that the TVH may be considered a potentially useful agent for redox balance in MetS conditions.
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出版者 University of Kragujevac, Faculty of Agronomy, Čačak (Serbia)