Preliminary study of oxidative stress biomarkers and trace elements in North Sea Harbour Seals
2021
Gismondi, Eric | Daneels, Lucienne | Damseaux, France | Lehnert, Kristina | Siebert, Ursula | Das, Krishna | FOCUS - Freshwater and OCeanic science Unit of reSearch - ULiège
英语. peer reviewed
显示更多 [+] 显示较少 [-]英语. This preliminary study investigated the potential correlations between trace elements (mercury, zinc, cadmium, copper, selenium, lead, nickel, chromium, lithium and vanadium) concentrations, measured in red blood cells, and oxidative stress biomarkers (total thiols, total glutathione, total and selenium-dependent glutathione peroxidases, triglycerides, malondialdehyde) assessed in the respective serum, in males and females P. vitulina, sampled in the Wadden Sea in spring and autumn 2015. Only concentrations of total mercury and zinc showed significant differences by sex, and only lipid peroxidation was different by season. Moreover, significant positive and negative correlations were observed between biomarkers (triglycerides, thiols, malondialdehyde, glutathione) and trace element concentrations (copper, lead, mercury, nickel, zinc). These findings suggest that the studied biomarkers could be useful for the assessment of oxidative stress in harbour seals exposed to trace elements, but further research with larger sample sizes is needed to better understand their specific associations.
显示更多 [+] 显示较少 [-]14. Life below water
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