WATER SOLUBLE CURCUMIN COMPOSITIONS FOR USE IN ANTI-CANCER AND ANTI-INFLAMMATORY THERAPY
2009
Neven, Philippe | Serteyn, Didier | Delarge, Jacques | Scheer, Eva | Kiss, Robert | Mathieu, Véronique | Cataldo, Didier | Rocks, Natacha | Université de Liège; Université Libre de Bruxelles | CORD - Centre de l'Oxygène, Recherche et Développement - ULiège
英语. publication date: 2011-10-20; filing date: 2009-05-26
显示更多 [+] 显示较少 [-]英语. The present invention relates to the medical field. In a first aspect the present invention relates to novel water soluble cyclodextrin-curcumin complexes having a pharmacological activity, in particular an anti-tumour and/or anti-inflammatory activity, and improved physico-chemical properties. In a second aspect, the present invention relates to a method for preparation of said water soluble curcumin derivatives. The invention further relates in a third aspect to a pharmaceutical composition comprising an effective amount of said water soluble curcumin derivatives. In a fourth aspect, the present invention concerns the use of said water soluble cucumin derivatives as a medicament and the use of said water soluble curcumin derivatives for the preparation of a medicament for the treatment of cancer and inflammatory diseases. In a fifth aspect, the present invention relates to the use of a pharmaceutical composition comprising said water soluble curcumin derivatives in the treatment of cancer and inflammatory diseases and to a new pharmaceutical composition comprising said water soluble curcumin derivatives.
显示更多 [+] 显示较少 [-]