Shedding light on the hidden benefit of Porphyridium cruentum culture
2023
Liberti, Davide | Imbimbo, Paola | Giustino, Enrica | D’Elia, Luigi | Silva, Mélanie | Barreira, Luísa | Monti, Daria Maria
Microalgae can represent a reliable source of natural compounds with different activities. Here, we evaluated the antioxidant and anti-inflammatory activity of sulfated exopolysaccharides (s-EPSs) and phycoerythrin (PE), two molecules naturally produced by the red marine microalga Porphyridium cruentum (CCALA415). In vitro and cell-based assays were performed to assess the biological activities of these compounds. The s-EPSs, owing to the presence of sulfate groups, showed biocompatibility on immortalized eukaryotic cell lines and a high antioxidant activity on cell-based systems. PE showed powerful antioxidant activity both in vitro and on cell-based systems, but purification is mandatory for its safe use. Finally, both molecules showed anti-inflammatory activity comparable to that of ibuprofen and helped tissue regeneration. Thus, the isolated molecules from microalgae represent an excellent source of antioxidants to be used in different fields.
显示更多 [+] 显示较少 [-]UIDP/0436/2020
显示更多 [+] 显示较少 [-]LA/P/0101/2020
显示更多 [+] 显示较少 [-]info:eu-repo/semantics/publishedVersion
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