<it>Brachyspira pilosicoli </it>bloodstream infections: Case report and review of the literature
2008
Brun-Buisson Christian | Legrand Patrick | Thille Arnaud | Bait-Merabet Lilia | Cattoir Vincent
<p>Abstract</p> <p><it>Brachyspira pilosicoli </it>is the etiologic agent of human and animal intestinal spirochetosis and is rarely implicated as a cause of bacteremia. Here, we describe the case of a <it>B. pilosicoli </it>spirochetemia in a 53-year-old male patient suffering from cardiogenic shock. This fastidious bacterium was isolated from blood, likely after translocation from the intestinal tract. Blood cultures were positive after 5 days of incubation (one day after the patient's death), highlighting the problem of the recovery of such type of fastidious bacterium. Identification was achieved by molecular methods (16S rRNA sequencing). A review of the English literature found only 8 cases of bacteremia caused by <it>B. pilosicoli</it>, mostly in immunocompromised or critically ill patients. Finally, difficulties in rapid and accurate diagnosis of <it>B. pilosicoli </it>bloodstream infections, in vitro antimicrobial susceptibility of human clinical isolates, and therapeutic options are discussed.</p>
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