Tiamulin fumarat – new makrolide on bovine mastitis therapy in vivo and in vitro
2020
Kriukova Vera | Kuznechova Nadezda | Gaponova Viktoriya | Sabyrzyanova Lilia
Antibiotics nowadays are widely used for the treatment of mastitis in cows, which, along with a positive effect, cause negative consequences to the organism of an animal, can be consumed by people and interacts the cultural qualities of microorganisms However, it is almost impossible to refuse from antibacterial therapy of mastitis with chemotherapy drugs. And the variety range of chemotherapy drugs for mastitis therapy today is very wide. Since we conduct monitoring devoted to full characteristics of the strains of Streptococcus spp., isolated from bovine mastitis milk of the geographical zone of Leningrad region, Russia. That is, we analyses received data on the cultural, microbiological, serological, virulence factors, and sensibility to main used in practice antibiotics and to new ones. Taking into account the already proven resistance of microorganisms to antibiotics, the biological industry offers antibacterial drugs based on new active substances for use in the treatment of cow mastitis. In the assay described in this paper, we set a goal-to investigate the antibacterial effect of tiamulin fumarat to clinical isolates of streptococci received from milk of cows with mastitis, and to determine its clinical efficacy on cows with mastitis of the bacteriological etiology
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