Improved metagenomic analysis with Kraken 2
2019
Derrick E. Wood | Jennifer Lu | Ben Langmead
Abstract Although Kraken’s k-mer-based approach provides a fast taxonomic classification of metagenomic sequence data, its large memory requirements can be limiting for some applications. Kraken 2 improves upon Kraken 1 by reducing memory usage by 85%, allowing greater amounts of reference genomic data to be used, while maintaining high accuracy and increasing speed fivefold. Kraken 2 also introduces a translated search mode, providing increased sensitivity in viral metagenomics analysis.
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书目信息
Genome Biology
卷
20
期
1
页码
1
- 13
ISSN
1474-760X
出版者
BMC
其它主题
Alignment-free methods; Minimizers; Metagenomics classification; Metagenomics; Probabilistic data structures
语言
英语
2024-12-11
DOAJ
