The claim that β-lactam antibiotics induce the SOS response, allowing E. coli survival in the presence of low antibiotic concentrations, was evaluated. No association between the recA gene and antibiotic survival rate was found. Disagreements with published observations are attributed to discrepancy in minimum inhibitory concentrations and growth characteristics of various strains carrying the recA mutation. Moreover, β-lactam antibiotics do not induce expression of the SOS regulated gene cka, encoding colicin K in wild-type strains.
显示更多 [+] 显示较少 [-]AGROVOC关键词
书目信息
出版者
University of Ljubljana Press (Založba Univerze v Ljubljani)
其它主题
Sos response; Β-lactam antibiotics; E. coli
语言
英语
2024-12-11
2026-02-03
DOAJ