Addressing Sexually Transmitted Infections Due to <i>Neisseria gonorrhoeae</i> in the Present and Future
2024
Julia Colón Pérez | Rosa-Antía Villarino Fernández | Adrián Domínguez Lago | María Mercedes Treviño Castellano | María Luisa Pérez del Molino Bernal | Sandra Sánchez Poza | Eva Torres-Sangiao
It was in the 1800s when the first public publications about the infection and treatment of gonorrhoea were released. However, the first prevention programmes were only published a hundred years later. In the 1940s, the concept of vaccination was introduced into clinical prevention programmes to address early sulphonamide resistance. Since then, tons of publications on <i>Neisseria gonorrhoeae</i> are undisputed, around 30,000 publications today. Currently, the situation seems to be just as it was in the last century, nothing has changed or improved. So, what are we doing wrong? And more importantly, what might we do? The review presented here aims to review the current situation regarding the resistance mechanisms, prevention programmes, treatments, and vaccines, with the challenge of better understanding this special pathogen. The authors have reviewed the last five years of advancements, knowledge, and perspectives for addressing the <i>Neisseria gonorrhoeae</i> issue, focusing on new therapeutic alternatives.
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