A COMPLETE NMR STUDY OF DOXAZOSIN CHARACTERIZATION
2017
Itamar Luís Gonçalves | Mariana Maier Gaelzer | Gabriel Oliveira de Azambuja | Christianne Gazzana Salbego | Vera Lucia Eifler-Lima
Doxazosin is an important drug used for treating hypertension and prostatic hyperplasia. An enantiomeric mixture (R)/(S) doxazosin mesylate was complete characterized by NMR and additionally FT-IR spectroscopy techniques. Were performed different NMR experiments, such as APT, HSQC, and HMBC in order to confirm the NMR signals assignments. All the hydrogens and the most of carbons atoms were assigned.
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出版者
Universidade Federal do Rio Grande do Sul
语言
英语
2024-12-12
2025-10-24
DOAJ