<i>Hibiscus sabdariffa</i>, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention
2021
Marwah Al-Anbaki | Anne-Laure Cavin | Renata Campos Nogueira | Jaafar Taslimi | Hayder Ali | Mohammed Najem | Mustafa Shukur Mahmood | Ibrahim Abdullah Khaleel | Abdulqader Saad Mohammed | Hasan Ramadhan Hasan | Laurence Marcourt | Fabien Félix | Nicolas Vinh Tri Low-Der’s | Emerson Ferreira Queiroz | Jean-Luc Wolfender | Marie Watissée | Bertrand Graz
In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP); medical treatments were often interrupted. The feasibility of using <i>Hibiscus sabdariffa</i> (<i>HS</i>) decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high blood pressure (BP) (≥140/90 mmHg) was conducted. Participants of the intervention group (with or without conventional medication) received <i>HS</i> decoction on a dose regimen starting from 10 grams per day. BP was measured five times over six weeks. The major active substances were chemically quantified. Results: After 6 weeks, 61.8% of participants from the intervention group (<i>n</i> = 76) reached the target BP < 140/90 mmHg, compared to 6.7% in the control group (<i>n</i> = 45). In the intervention group, a mean (±SD) reduction of 23.1 (±11.8) mmHg and 12.0 (±11.2) for systolic and diastolic BP, respectively, was observed, while in the control group the reduction was 4.4 (±10.2)/3.6 (±8.7). The chemical analysis of the starting dose indicated a content of 36 mg of total anthocyanins and 2.13 g of hibiscus acid. The study shows the feasibility of using HS decoction in IDP’s problematic framework, as hibiscus is a safe, local, affordable, and culturally accepted food product.
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