Potential role of macrophage migration inhibitory factor in the pathogenesis of Marek’s disease

Fan Zhongjun; Wang Huanli; Pan Jiahao; Yu Shupei; Xia Wenlong

Potential role of macrophage migration inhibitory factor in the pathogenesis of Marek’s disease

2020

Fan Zhongjun | Wang Huanli | Pan Jiahao | Yu Shupei | Xia Wenlong

Marek’s disease virus (MDV) can cause malignant T-cell lymphomas and immunosuppression in chickens. Macrophage migration inhibitory factor (MIF) not only plays a critical role in inhibiting T-cell responses, but also contributes to multiple aspects of tumour progression. The aim of this study was to reveal the potential role of MIF in the pathogenesis of MDV infection.

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