The g. -442 G>C polymorphism in the promoter region of the Prophet of Pit-1 gene is associated with litter size at early parities in sows
2014
Mizoguchi, Y. (Meiji University, Kanagawa (Japan). School of Agriculture) | Yoshikawa, S. | Saito, S.
Four novel polymorphisms were identified in a 2.3-kb region spanning the proximal promoter of the swine Prophet of Pit-1 (PROP1) gene. We conducted association analysis between polymorphisms in the promoter region of the PROP1 gene and reproductive traits in sows. We genotyped 267 Landrace * Large White crossbred sows and conducted the association analysis using 10 reproductive traits for first and second parities. In this population, the C allele of the g. -442 G>C SNP was associated with significantly greater numbers of total pigs born and pigs born alive (PBA) in parity 1, and with higher summed PBA in parity 1 and 2 (P< 0.05). These results suggest that the g. -442 G>C SNP in the promoter region of the PROP1 gene affects reproductive traits at early parities in sows.
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