FLUORESCENCE STUDY OF BSA INTERACTION WITH (R)-5-(3-(4-(AZEPAN-1-YLMETHYL)-1H-1,2,3-TRIAZOL-1-YL)PROP-1-EN-2-YL)-2-METHYLCYCLOHEX-2-ENONE
2018
Ghazaryan, A.G.
Interaction between bovine serum albumin (BSA) and (R)-5-(3-(4-(azepan-1-ylmethyl)-1H-1,2,3-triazol-1-yl)prop-1-en-2-yl)-2-methylcyclohex-2-enone (Triazole-A) was studied at 298 K and 308 K using fluorescence spectroscopy method. It was shown that the quenching mechanism of BSA by Triazole-A was initiated by a dynamic collision. Synchronous fluorescence measurements indicate that binding between Triazole-A and the protein does not lead to a change in the polarity of the microenvironment of the tryptophan and tyrosine residues.
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出版者
Yerevan State University
其它主题
Triazole-a; Fluorescence spectroscopy; Synchronous fluorescence; Bovine serum albumin
语言
英语
格式
application/pdf
许可
Copyright (c) 2018 Proceedings of the YSU, https://creativecommons.org/licenses/by-nc/4.0/
ISSN
2953-7983, 1829-1767
类型
Info:eu-Repo/semantics/article; Info:eu-Repo/semantics/publishedversion
来源
Proceedings of the YSU B: Chemical and Biological Sciences; Vol. 52 No. 1 (245) (2018); 20-23, ԵՊՀ Գիտական տեղեկագիր. Քիմիական և կենսաբանական գիտություններ; Հտ․ 52 Հմր․ 1 (245) (2018); 20-23, ԵՊՀ Գիտական տեղեկագիր. Քիմիա և կենսաբանություն; Հտ․ 52 Հմր․ 1 (245) (2018); 20-23, Ученые записки ЕГУ: химические и биологические науки; Том 52 № 1 (245) (2018); 20-23, 2953-7983, 1829-1767, 10.46991/PYSUB.2018.52.1
2025-01-20
Dublin Core
