The influence of salinity on the fate and behavior of silver standardized nanomaterial and toxicity effects in the estuarine bivalve Scrobicularia plana
2016
Bertrand, Carole | Zalouk-Vergnoux, Aurore | Giambérini, Laure | Poirier, Laurence | Devin, Simon | Labille, Jérôme | Perrein-Ettajani, Hanane | Pagnout, Christophe | Châtel, Amélie | Levard, Clément | Auffan, Melanie | Mouneyrac, Catherine | Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC) ; Institut national des sciences de l'Univers (INSU - CNRS)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS) | Mer, molécules et santé EA 2160 (MMS) ; Le Mans Université (UM)-Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST) ; Université de Nantes (UN)-Université de Nantes (UN)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques (UFR SPB) ; Université de Nantes (UN)-Université de Nantes (UN) | International Consortium for the Environmental Implications of Nanotechnology (iCEINT), Aix en Provence, France | Centre Européen de Recherche et d'Enseignement des Géosciences de l'Environnement (CEREGE) ; Institut de Recherche pour le Développement (IRD)-Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Collège de France (CdF (institution))-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS) | Mer, Molécules, Santé - EA 2160 - Le Mans (MMS) ; Le Mans Université (UM) | Mer, molécules et santé (MMS UCO) ; Université Catholique de l'Ouest (UCO)-PRES Université Nantes Angers Le Mans (UNAM) | ANR-13-CESA-0014,nanoSALT,Nanomatériaux à travers un gradient de salinité: exposition et effets ecotoxicologiques au cours de leur cycle de vie (production, utilisation, fin de vie)(2013) | European Project: 310584,FP7-NMP-2012-LARGE-6,FP7-NMP-2012-LARGE-6,NANOREG(2013)
International audience
显示更多 [+] 显示较少 [-]英语. ĂBecause of their antibacterial properties, silver (Ag) engineered nanomaterials are included in many products. The present study used a standardized Ag nanomaterial (NM-300K, 20 nm) supplied with a stabilizing agent. The aim was to investigate the behavior of Ag nanomaterial in an estuarine-like medium at 2 salinities (15 psu and 30 psu). Uptake as well as sublethal effects of Ag nanomaterial (10 μg Ag/L), its stabilizing agent, and AgNO3 (10 μg Ag/L) were assessed in the clam Scrobicularia plana, after 7 d of exposure. The release of soluble Ag from Ag nanomaterial in the experimental media was quantified by using diffusive gradient in thin films and ultrafiltration. A multibiomarker approach was employed to reveal responses of clams at subindividual and individual levels. The bioaccumulation of Ag was significantly greater at 15 psu versus 30 psu, which could be explained by differences in Ag speciation. In conclusion, the present study showed different impacts of Ag nanomaterial that were not always explained by the release of Ag ions in clams at both salinities; such impacts were particularly characterized by induction of oxidative stress, cell damage, and impairment of energetic levels. Burrowing of clams was affected by the stabilizing agent depending on the salinity tested, with stronger effects at 15 psu. Finally, the present study highlighted salinity-dependent changes in the physiology of estuarine bivalves. Environ Toxicol Chem 2016;35:2550–2561. © 2016 SETAC
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