Relationship Between Preoperative Inflammation Ratios Derived From Preoperative Blood Cell Count and Postoperative Pulmonary Complications in Patients Undergoing Lobectomy: A Single-Center Observational Study
2023
de Fréminville, Amaury | Saad, Mary | Sage, Édouard | Pricopi, Ciprian | Fischler, Marc | Trillat, Bernard | Salze, Benjamin | Pascreau, Tiffany | Vasse, Marc | Vallée, Alexandre | Guen, Morgan Le | Fessler, Julien | Hôpital Foch [Suresnes] | Université de Versailles Saint-Quentin-en-Yvelines (UVSQ) | Department od Anesthesiology Hopital Foch [Suresne] | Cancer et génome: Bioinformatique, biostatistiques et épidémiologie d'un système complexe ; Mines Paris - PSL (École nationale supérieure des mines de Paris) ; Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM) | Virologie et Immunologie Moléculaires (VIM (UR 0892)) ; Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Chirurgie thoracique et transplantation pulmonaire [Suresnes] (CT2P - Hôpital Foch) ; Hôpital Foch [Suresnes] | Department of Anesthesiology, Hopital Foch [Suresne] | Department of Information Systems Hopital Foch Suresne | Department of Anesthesiology, Hôpital Foch [Suresne] | Hémostase, Inflammation, Thrombose (HITH - U1176 Inserm - CHU Bicêtre) ; Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre] ; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Saclay | Department of Clinical Biology, Hôpital Foch, Suresnes | Direction de la Recherche Clinique et de l'Innovation [AP-HP] (DRCI) ; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
International audience
显示更多 [+] 显示较少 [-]英语. AbstractObjective: Evaluation of the association of inflammatory cell ratios, especially neutrophil-to-lymphocyte ratio (NLR), based on preoperative complete blood counts, with postoperative complications in lobectomy surgery.Design: This was a retrospective monocentric cohort study.Setting: The study was conducted at Foch University Hospital in Suresnes, France.Participants: Patients having undergone a scheduled lobectomy from January 2018 to September 2021.Interventions: There were no interventions.Measurements and main results: The authors studied 208 consecutive patients. Preoperative NLR, monocyte-to-lymphocyte ratio, platelet-to-lymphocyte ratio, systemic inflammation index, systemic inflammation response index, and aggregate inflammation systemic index were calculated. Median and (IQR) of NLR was 2.67 (1.92-3.69). No statistically significant association was observed between any index and the occurrence of at least one major postoperative complication, which occurred in 37% of the patients. Median postoperative length of stay was 7 (5-10) days. None of the ratios was associated with prolonged length of stay (LOS), defined as a LOS above the 75th percentile.Conclusions: The results suggested that simple available inflammatory ratios are not useful for the preoperative identification of patients at risk of postoperative major complications in elective lobectomy surgery.
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