Improvement of disease resistance by genetic methods
2017
Robinson, Nicholas Andrew | Gjedrem, Trygve | Quillet, Edwige | Norwegian Institute of Food,Fisheries and Aquaculture Research (NOFIMA) | University of Melbourne | Génétique Animale et Biologie Intégrative (GABI) ; Institut National de la Recherche Agronomique (INRA)-AgroParisTech | Université Paris-Saclay | Galina Jeney
Chapitre 2
显示更多 [+] 显示较少 [-]英语. Populations of fish and shellfish show a wide variability in their ability to tolerate or resist infectious diseases. For most species and diseases studied to date, a significant component of this variability is genetically determined, heritable, and affected by many genes. Quantitative genetic and animal breeding principles, accounting for the unique biology and culture conditions for aquatic species, can therefore be applied to produce populations with greater resistance or tolerance, and great progress has been made so far. High-throughput sequencing, genomic selection, and other new technologies or methodologies have great potential for improving accuracy and speeding the rate of genetic improvement of disease resistance, identifying genes with potential immune function and increasing knowledge about mechanisms affecting immunity. By reducing the overall impact of disease on farm economics, and reducing reliance on antibiotics and chemical treatments, genetic improvement strategies are of key importance for the future sustainability of world aquaculture.
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