Towards a Structural Basis for the Relationship Between Blood Group and the Severity of El Tor Cholera
2012
Mandal, Pintu K. | Branson, Thomas R. | Hayes, Edward D. | Ross, James F. | Gavín, José A. | Hernández Daranas, Antonio | Turnbull, W. Bruce | Engineering and Physical Sciences Research Council (UK) | Ministerio de Ciencia e Innovación (España) | AstraZeneca | Wellcome Trust
It has long been known that people with blood group O are more severely affected by El Tor cholera than those with blood groups A or B. Microcalorimetry and NMR spectroscopy are used to evaluate the ability of the B‐subunits of cholera toxin and E. coli heat‐labile toxin to bind to selected blood group oligosaccharides.
显示更多 [+] 显示较少 [-]Peer reviewed
显示更多 [+] 显示较少 [-]