Bacteriophages as weapons against bacterial biofilms in the food industry
2016
Gutiérrez, Diana | Rodríguez, Lorena | Martínez Fernández, Beatriz | García Suárez, María Pilar | Ministerio de Ciencia e Innovación (España) | European Commission | Principado de Asturias
Microbiological contamination in the food industry is often attributed to the presence of biofilms in processing plants. Bacterial biofilms are complex communities of bacteria attached to a surface and surrounded by an extracellular polymeric material. Their extreme resistance to cleaning and disinfecting processes is related to a unique organization, which implies a differential bacterial growth and gene expression inside the biofilm. The impact of biofilms on health, and the economic consequences, has promoted the development of different approaches to control or remove biofilm formation. Recently, successful results in phage therapy have boosted new research in bacteriophages and phage lytic proteins for biofilm eradication. In this regard, this review examines the environmental factors that determine biofilm development in food-processing equipment. In addition, future perspectives for the use of bacteriophage-derived tools as disinfectants are discussed.
显示更多 [+] 显示较少 [-]This research study was supported by grants AGL2012-40194-C02-01 (Ministry of Science and Innovation, Spain), GRUPIN14-139 (Program of Science, Technology and Innovation 2013–2017 and FEDER EU funds, Principado de Asturias, Spain) and bacteriophage network FAGOMA.
显示更多 [+] 显示较少 [-]Peer Reviewed
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