Effect of hyperprolactinemia in animal production – a review

英语. Hyperprolactinemia is a hormonal dysfunction that may have physiological, pathological, functional and pharmacological origin. Hyperprolactinemia describes the state of prolonged elevated levels of prolactin, exceeding the physiological norm adopted for a given species. This particular dysfunction is well known in humans. High concentrations of prolactin are also the cause of false pregnancy. In mares, it is the likely cause of fertility problems. Irregularities in ovarian cycles in turn mean difficulties in determining the best timings for artificial insemination and natural mating. Due to the large number of prolactin isoforms, laboratory methods for prolactin level measurement may lead to falsified results, and thus also to misdiagnosis. Drug treatment consists in administration of D2 receptor agonists. Despite the research conducted, the treatment of hyperprolactinemia is not simple, and the disease results in financial losses incurred by animal farmers.

英语. hyperprolactinemia, PRL, fertility

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