Isolation and molecular characterization of Lactobacillus delbrueckii subsp based on bulgaricus strain 1 from kefir shows probiotic and antimicrobial properties: Linking probiotics to UNSDG (United Nations Sustainable Development Goals) agenda: 2030
2025
K. Z. Tleuova | A. U. Shingisov | B. M. Khamitova | E. T. Kanseitova | A. K. Tulekbaeva
Abstract The global population increase necessitates the dire need for ample food as medicine. Good health and well-being are stressed on probiotic functional foods. The present study characterizes biochemical and molecular identification of potential lactic acid bacteria. The potent antimicrobial properties also affirm Lactobacillus delbrueckii subsp. bulgaricus strain 3286. Biochemical analysis comprises carbohydrate fermentation, tolerance to acids and bile salts, production of bioactive compounds, lecithinase production, gelatinase production, and strain ripening ability. Antibiotic sensitivity to various antibiotics was assessed employing minimum inhibitory concentration (MIC) and E-test. Strain resistance to increased salt concentrations coherently concludes the positive impact of gut microbiome and gut-brain axis health management. The preliminary assessment requires further in vitro, in vivo, and in silico analysis for commercialization, market strategy and utility as functional food supplementation. The study can be rationalized for sustainable development goals regarding SDG 3: good health and well-being. Further, the UNSDG agenda 2030 also ascertains the role of probiotic foods in life longevity and public health management systems.
显示更多 [+] 显示较少 [-]