A receptor-based assay to study bitterness masking effect of yeast extracts
2021
Belloir, Christine | Thomas, Antoine | Menin, Rudy | Briand, Loïc | Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA) ; Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Université Bourgogne Franche-Comté [COMUE] (UBFC) | Biospringer by Lesaffre
Online event (Live and on-demand). Open access conference indexed in OpenAIRE.
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显示更多 [+] 显示较少 [-]英语. Yeast extracts (YEs) are widely used by the food industry for the formulation of foods and beverages, as they bring a natural combination of flavour molecules, including aroma-active and non-volatile compounds (taste-active compounds). Adding a touch of umami, some richness or a typical flavour signature, YEs are used as ingredients to mask the bitterness of some food products. In the present work, using functional calcium mobilization assays, we demonstrated the ability of two different YEs (YE1 and YE2) and the ribonucleotide adenosine 5’ monophosphate (AMP) to stimulate heterologously expressed human bitter taste receptors named TAS2Rs. We then observed that YE1 inhibits the response of two TAS2Rs stimulated by control agonists. Our data demonstrate that the bitterness masking effect of YEs is a molecular mechanism occurring at the receptor level.
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