HISTOPATHOLOGIC STUDY OF THE HEPATIC AND RENAL LESIONS INDUCED BY EXPERIMENTAL TOXIC DIETARY APPLICATION OF AFLATOXIN B; IN BROILER CHICKS
2005
am Bader Falih | Ena
The present study investigated the toxicologic histopathologie effect ofallatoxin Hi, 60 broiler chicks ol’ one-day aged devided randomly and equally into three groups. for dietary study, using one group as untreated control, while the other groups were given aflatoxin B. mixed with diet in concentration of 0.5 and 1.5 ppm respectively, for 30 days, the study showed fatty degeneration of liver associated with bile duct prolilicration, accompanied by infiltration of monenuclcar cells and lymphocytes. Also there was degeneration in proximal convoluted tubules mostly as hyaline degeneration especially at 0.5 ppm dose level. Those at 1.5 ppm dose level, there was focal liver cell necrosis associated with fibrosis and enlarged proliferated bile ducts. sever vacuolation and necrosis of epithelial of renal proximal convoluted tubules with thickening of the glomerular basement membrane
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