EFFECT OF LIDOCAINE , DICLOFENAC AND THEIR MIXTURE ON SOME BLOOD PARAMETERS IN EXPERIMENTAL MICE
2007
Shereen jawad khadium Ali
The study included the evaluation of tire haematological effects resulting from intramuscular injection of ( 1 mg/kg ) of Li! ocaine (group A) , Diclofenac (group B) and Lidocaine — Diclofenac mixture (group in experimental mice , as a result there was a significant decrease in haemoglobin dpncentration and reached it's lowest value in group C ( 7.04 gm/100ml ) . There was also a significant increase in both total WBCS cpunt and eosinophils number reached it's highest number in group C ( 9.88 X 103/mm’ , ll.2 % ) respectively , while the highest number basophils appeared in group B and reached ( 8 % ) , the same group showed a significant decrease in neutrophils number which reached to ( 17.6 % ) . the a granulocytes ( lymphocytes and monocytes ) showed no changes in number in all groups .
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