EFFECT OF LOW LEVEL LASER AND CHITOSAN POWDER ON THE ACCELIRATION OF WOUND HEALING IN RABBITS
2010
N. M. AL-Hayani
Open wounds have lost the barrier that protects tissues from bacterial invasion and allowfor the escape of vital fluids. The purpose of this study is to evaluate the enhancing oftherapeutic effect of Low Level Laser (LLL) and chitosan on the acceleration of openwound healing. Forty two adult rabbits were used. They divided into three equal groups (I,II and III). Wound was produced at the dorsal region by remove all thickness of skin atwidth of 3.5cm and of length 4 cm. Group I was left without treatment, while chitosanpowder and laser therapy were used in group II and III respectively. Results of two groupswere compared with control group. Histpathologicl results at the period of 3, 7, 14, 21 and28 days post operation reflected the presence of large number of fibroblast with formationof new blood vessels, also the collagen fiber become dense and regular in 14 days postoperation in irradiated groups. In 21days there was formation of new and normal epidermalclosed the rupture area of III group.
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