Epidemiological and clinical profiles of young and senior dogs fed a standard diet
2025
Blanchard, Tiphaine | Mugnier, Amélie | Boulet, Fleur | Meynadier, Annabelle | Priymenko, Nathalie | Génétique Physiologie et Systèmes d'Elevage (GenPhySE) ; Ecole Nationale Vétérinaire de Toulouse (ENVT) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-École nationale supérieure agronomique de Toulouse (ENSAT) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Lallemand SAS | Prévention et promotion de la cancérogénèse par les aliments (ToxAlim-PPCA) ; ToxAlim (ToxAlim) ; Université Toulouse III - Paul Sabatier (UT3) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | This study was partially funded by Lallemand SAS (Blagnac, France) and supported by Melet Schloesing Laboratories Inc (Osny, France), which provided all the resources needed for biochemistry measurements.
International audience
显示更多 [+] 显示较少 [-]英语. This study aimed to explore age-related differences in epidemiological and clinical parameters in dogs consuming a standardized diet, focusing on factors relevant to veterinary practitioners. A total of 106 dogs were included, comprising young (2-5 years) and senior (≥8 years) individuals. Epidemiological data were collected through questionnaires and veterinary consultations, while clinical parameters were assessed via physical examinations and blood analyses. Compared to younger dogs, senior dogs were less active, more likely to live in houses, and more frequently received regular deworming. They were also more likely to consume food purchased from pet stores or supermarkets compared to younger dogs. Clinical evaluations revealed that senior dogs had higher plasma globulin and platelets and lower albumin, consistent with chronic low-grade inflammation associated with aging. Muscle loss, poor coat quality, and reduced lymphocyte counts were also prominent in senior dogs, potentially reflecting sarcopenia, malnutrition, and immunosenescence, respectively. Notably, dogs previously fed diets lacking a source of omega-3 fatty acids exhibited elevated plasma triglycerides even after transitioning for four weeks to a premium diet containing fish oil, underscoring the lasting impact of long-term dietary habits. These findings highlight the importance of regular veterinary follow-ups for senior dogs and the role of highquality nutrition, including sources of omega-3 fatty acids. By identifying key epidemiological and clinical differences, this study offers valuable insights to help veterinary practitioners distinguish between healthy and pathological aging.
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