Serotonin is an omnipotent molecule in the brain and rest of the body and plays a pivotal role in the gut-brain axis.Serotonin’s role in neurotransmission and its function at molecular levels with different genetic variants has beenwidely covered across the animal kingdom. Although the digestion process in ruminants is pillared on anaerobicmicroflora present in the rumen, the impact of the rumen microbial population on serotonergic activity is seldomexplored. Besides its principal effect on the gastrointestine, it regulates the excretion of bile acids, glucose and lipidhomeostasis, energy balance, immunomodulation, and various other vital processes in the animal system. However,the studies on part of peripheral serotonin are moderate and very few in bovines. The objective of this review is toappreciate research conducted on the basics of serotonin, triallelic polymorphism in SLR6A4 gene polymorphism,receptors and its role in GI, liver, pancreas, adipocytes, and to a little extent in other organs like uterus, mammarygland, etc. in different species and look forward to expanding the information in bovines.
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AGRIS - 国际农业科技情报系统
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出版者
Indian Council of Agricultural Research
其它主题
Contractions; Peripheral
语言
英语
格式
application/pdf
许可
Copyright (c) 2022 The Indian Journal of Animal Sciences, https://creativecommons.org/licenses/by-nc-sa/4.0
类型
Journal Article; Journal Part; Info:eu-Repo/semantics/publishedversion; Journal Article; Journal Part
来源
The Indian Journal of Animal Sciences; Vol. 92 No. 9 (2022); 1033-1040, 2394-3327, 0367-8318
2025-09-02
Dublin Core