Phytochemical and biological activity screening of plants collected from Kuala Keniam, Taman Negara, Pahang
2010
Rohaya Ahmad | Faridahanim Mohd Jaafar | Noor Hana Hussain | Nor Hadiani Ismail | Norizan Ahmat | Shamsul Khamis
Tropical plants with diverse chemical complexities are undoubtedly the most important natural resource in the search for bioactive natural products with potential use in pharmaceutical applications and healthcare. Seventy-six plant species of interest from twenty-five families were collected during two phytochemical expeditions in Kuala Keniam, Pahang. The plants were from family Rubiaceae, Annonaceae, Lecythidaceae, Myristicaceae, Tiliaceae, Rosaceae, Moraceae, Ulmaceae, menispermaceae, Euphobiaceae, Lauraceae, Ebenaceae, Verbanaceae, Myrsinaceae, Simaroubaceae, Leeaceae, Rutaceae, Melastomaceae, Sterculiaceae, Celastraceae, Commelinaceae, Burseraceae, Convolvulaceae, Guttiferae and Pandanaceae. The plants were screened on site for presence of alkaloids and flavonoids. Several plants with high content of alkaloids and flavonoids were found. Alkaloids and flavonoids are classes of compounds with many therapeutic activities such as antioxidant, antimicrobial, anticancer and others. A total of 143 extracts produced from various parts of the plants were evaluated for free radical scavenging and antimicrobial activities. Several plants with strong free radical scavenging activity and good antimicrobial activity were identified. Detailed phytochemical studies of the potential plants may lead to the isolation of interesting bioactive molecules which may become a platform for development of various useful commercial healthcare products and pharmaceuticals form our tropical plants.
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