Melissa officinalis L. (Lemon Balm): Flavonoid Composition and Antioxidant Properties
2025
Huseynova, A.
Melissa officinalis L. belongs to the genus Melissa L. (commonly known as lemon balm) of the family Lamiaceae Martynov. This plant, possessing strong pharmacological properties, has been extensively studied in several countries, including Turkey, Iran, Algeria, France, Germany, Italy, Romania, Bulgaria, North America, and many others. To analyze the harmonization of the effects of Melissa officinalis L. in folk medicine and modern medical science and to strengthen the flavonoid content of the plant cultivated by the population in the Nakhchivan Autonomous Republic. Because polyphenol and flavonoid compounds have a special role in each pharmacological effect. Plant material of Melissa officinalis L. was obtained from a private household in the Ordubad district of the Nakhchivan Autonomous Republic. The study was conducted at the Biomedicine Center of Nakhchivan State University. Extracts were prepared separately from the leaves and flowers of the plant using 70% ethanol. The total flavonoid content was determined using the colorimetric method described by Fukumoto and Mazza. The total flavonoid content in the leaves of M. officinalis L. was determined to be 6.1777±0.466969 mg quercetin equivalents per g of dry sample, while in the flowers it was approximately two times lower — 3.5557±0.2688 mg QE/g dry sample. Collecting up-to-date scientific data on the medicinal properties of Melissa officinalis L. and studying its flavonoid composition in relation to the region of cultivation will facilitate future research on the extraction process and promote the broader application of this plant in medicine and pharmacology.
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