Phenotypic and genotypic profile of clinical and animal multidrug-resistant Salmonella enterica isolates from Mexico
2017
AGUILAR MONTES DE OCA, SAUL; 443652 | TALAVERA ROJAS, MARTIN; 111873 | SORIANO VARGAS, EDGARDO; 39642 | BARBA LEON, JEANNETTE; 39967 | VAZQUEZ NAVARRETE, JESUS; 120644 | ACOSTA DIBARRAT, JORGE PABLO; 229114 | SALGADO MIRANDA, CELENE; 261083 | AGUILAR MONTES DE OCA, SAUL | TALAVERA ROJAS, MARTIN | SORIANO VARGAS, EDGARDO | BARBA LEON, JEANNETTE | VAZQUEZ NAVARRETE, JESUS | ACOSTA DIBARRAT, JORGE PABLO | SALGADO MIRANDA, CELENE
Descripción de Salmonella enterica multirresistente
显示更多 [+] 显示较少 [-]Aims: The objective of this study was to obtain a phenotypic and genotypic profile of Salmonella enterica including multidrug-resistant (MDR) isolates from food-producing animals and clinical isolates, as well as their genetic relatedness in two different States of Mexico (Jalisco and State of Mexico). Methods and Results: A total of 243 isolates were evaluated in terms of antimicrobial resistance (AMR) and related genes through a disk diffusion method and PCR respectively; we found 16 MDR isolates, all of them harbouring the blaCMY gene but not qnr genes, these isolates represent less than 10% of the collection. The pulsed-field gel electrophoresis revealed a higher genotypic similitude within isolates of State of Mexico than Jalisco. Conclusions: A low percentage of Salmonella isolates were resistant to relevant antibiotics in human health, nevertheless, the AMR and involved genes were similar despite the different serovars and origin of the isolates. Significance and Impact of the Study: This investigation rovided an insight of the current status of AMR of Salmonella isolates in two States of Mexico and pinpoint the genes involved in AMR and their epidemiological relationship, the information could help to determine an adequate therapy in human and eterinary medicine.
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