The role of lipid peroxidation in the pathogenesis of liver diseases in sows was studied. The state of the antioxidant system in these diseases was also assessed. The liver of sows has been examined after slaughter. There were four groups formed: healthy, acute and chronic hepatosis (HS), and liver cirrhosis. An increase in the level of endogenous intoxication has established, the content of primary (diene conjugates), secondary (malondialdehyde, ketodienes, ketotrienes), and final (Schiff base) products of lipid peroxidation in the blood of sows with hepatopathy. Also noticed that sows with hepatopathy had decreased antioxidant protection, catalase activity, and concentration of tocopherol and ascorbic acid. The level of change was growing with a gravity of hepatopathy. The most expressed disturbance has been observed in sows with liver cirrhosis.

In this article, we present the course and results of scientific research aimed at calculation of the concentration of somatic cells in cow's milk to detect subclinical mastitis in individual farms of the Republic of Armenia. Comparison of somatic cell concentrations in milk from healthy and sick cows with subclinical mastitis, analysis and comparison of blood morphological parameters in sick and healthy animals has been implemented and the relationship between somatic cell concentration in milk and morphological abnormalities in sick cow blood has been identified. SC concentrations between 300 and 500 thousand/ml are indicative of mastitis risk. In this case, the type of reaction manifested was positive. It was found that the viscosity of the investigated solution "Somatic plus" + milk increases in proportion to the increasing concentration of somatic cells in the milk sample, which indicates subclinical mastitis. A study of the morphological parameters of blood in healthy and subclinical mastitis animals revealed some deviations from the reference values of blood parameters, leading to the conclusion that these changes in animals' blood are related to an increase in the number of milk's somatic cells. Increased leukocytes were found in sick animals' blood. This was followedby an increase in stab neutrophils, eosinophils, monocytes, lymphocytes, and ESR. As a result of all this, the body is experiencing inflammatory processes mobilizing its defensive mechanisms against pathogens.

The research aimed to identify latent mastitis in cows on farms in the Republic of Armenia by counting somatic cells in milk using the California method. Among the 170 animals examined, 60 had latent mastitis, which comprised 35.2 % of the population. The highest incidence was observed in the Vayoc Dzor region (50 %), while the lowest was found in the Sunik region (25 %). It was found that 40 animals (23.5 %) showed a pronounced reaction to mastitis, and the concentration of somatic cells in milk was 300-500 thousand/sm3. 20 animals demonstrated a positive reaction to the test (11.7 %), and the number of somatic cells in milk exceeded 500 thousand/sm3. A microbiological study of milk from animals with subclinical mastitis was conducted to determine the species composition of pathogenic microflora. The study indicated that the milk was highly contaminated with staphylococcus, streptococcus, corynebacterial, E. coli, mycoplasma, candida, etc. A rise in leukocytes was observed in the blood of sick animals, as well as increases in band neutrophils, eosinophils, monocytes, lymphocytes, and ESRs. All this indicates, there is an inflammatory process present in the body and the immune system is mobilizing to fight pathology.

Latent mastitis harms the health of animals, their milk production, and the quality of milk. In cows affected by this disease sharp changes in hematological parameters, and biochemical parameters of blood and milk, which is the focus of our research. This work studies the morphological and biochemical parameters of blood and the biochemical parameters of milk in dairy cows affected by latent mastitis. The research was performed in several farms and farm households of Kotayk and Ararat regions, as well as in the ANAU Research Center of Veterinary Medicine and Veterinary Sanitary laboratories. The research outcomes prove that latent mastitis significantly impacts the composition of blood and milk components. Data obtained during the research enables a better understanding of the causes of mastitis as well as the necessity of using informative diagnostic methods in farm veterinarians’ practices.