Two 8-week old Aseel chicks were presented for necropsy from a native chicken farm with the history of swollen left eyelid, dyspnoea, off feed, dullness and sudden death. Gross examination of the carcasses revealed swollen left eye with cheesy exudate on incision. Lungs revealed severe congestion, with multifocal grey consolidated areas (1-2 mm diameter) while, the intestinal lumen was clogged by numerous round worms. Histopathological examination of lungs revealed multifocal granulomatous area with central necrosis, presence of macrophages, lymphocytes and multinucleated giant cells. Special staining with Periodic acid Schiff and Grocott-Gomori’s methenamine silver stain showed the presence of fungal hyphae and spores in the lung lesions. The fungus was identified as Aspergillus sp. by cultural examination. Intestines revealed numerous cut sections of worms with eosinophilic and mononuclear cell infiltration and were identified as Ascaridia galli. Eye lesion had multifocal mild to moderate mononuclear cell infiltration with osseous metaplasia of scleral cartilage in eyeball. Staphylococcus hyicus was isolated from the eye exudate by cultural examination. Etiological diagnosis revealed an outbreak of Aspergillosis, Ascariasis and Staphylococcal blepharitis in the farm.

Ascaris suum, Trichuris suis, naturally infected 10-week-old female pigs, anthelmintic activity of ivermectin administered subcutaneously or orally

Toxocara canis, cynomolgus macaques (exper.), visceral larva migrans, hematologic and serologic changes, neurologic signs, diminished growth rates, diagnostic antibody titers in enzyme-linked immunosorbent assay, severe granulomatous hepatitis and encephalomyelitis, no ocular lesions, basis for clinical interpretation and diagnosis in humans

evaluation of a Toxocara canis blastogenesis assay with peripheral mononuclear cells in Macaca fascicularis with induced T. canis infections and in humans with serologically confirmed visceral larva migrans (VLM), questionable sensitivity, difficulty, expense, and time associated with this technique do not make it suited for confirming a clinical diagnosis of VLM