Authors evaluated retinal toxicity produced by intraocular injection of kainic acid in 10 ducks to provide further informations on the kainic acid induced retinal lesions in the avian species. By 8 hrs after injection there were severe vacuolar degenerations in the inner plexiform layer and the inner portion of the inner nuclear layer; by 24 hrs after injection many of the cells exhibited pyknotic nuclei in the inner nuclear layer; by 48 hrs after injection the reduction in the thickness was apparent in this layer because of the partial loss of the pyknotic cells. By 96 hrs there were only a few cells in the center and inner protion of the inner nuclear layer; by 10 days there was a conspicuous decrease in the thickness of the inner nuclear layer and the inner plexiform layer

An experiment was carried out to measure the cellular immune response in the animals by sensitizing the animals with 2, 4-dinitrochlorobenzene (DNCB). The fowls could be sensitized with primary application of DNCB. The sensitizing and challenge dose was standarized. Heterophils were prominent in the early inflammatory response in the superficial and deep dermal regions with scattering of eosinophils. The histological response in the fowls was characteristic of a delayed hypersensitivity reaction