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Effect of hyaluronic acid on prevention of adhesion in rats
Lee, J.H.;Lee, J.M.;Yun, Y.M.;Kang, T.Y.;Woo, H.C.;Kang, Y.H.;Kim, H.S.;Lee, K.K.;Cheong, J.T.(Cheju National University, Jeju, Republic of Korea)E-mail:cjt123@cheju.ac.kr | Kim, N.J.(HyeChon College, Daejeon, Republic of Korea)
This study was conducted to investigate the effect of hyaluronic acid (HA) on prevention of abdominal adhesions depending on various concentrations thereof by inducing an abrasion experimentally in the cecum of rats. Each group was consisted of 10 rats, and 40 rats were divided into 4 groups comprising the saline treatment group, HA 0.4% treated group, 0.6% treated group, and 0.8% treated group. And abrasion was caused in the cecum by using dry gauze and thereby, adhesion was induced. On 7 days after the operation, adhesions of each region were evaluated into the range of 0~4.
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