Research results showed that in the conditions of correct organization and application of technological methods of livestock breeding and feeding it was possible to achieve high livability rate of sheep and lambs up to 90%. Also it was possible to get a substantial break of infection chain of many sheep diseases (especially those which had a respiratory nature). Research results showed that simultaneous application of convalescent-phase serum against sheep acute respiratory diseases, as well as Nitox 200 and Invamek for treatment of sheep and especially 2-3 month old lambs with respiratory infectious diseases promoted the recovery of 80-100% of animals.

In the conditions of immunization of swine by experimental produced at Vitebsk Biofactory in the Republic of Belarus vaccines in blood of experimental swine there stated the morphological changes which pointed to formation of immune response.

After immunization of 30-35 day old piglets against a salmonellosis, pasteurellosis and streptococcosis (SPS) with special produced in the Republic of Belarus SPS vaccine in combination with immunostimulant sodium thyosulfate and vitamin C there was observed an activation myeloblastic hemopoiesis and lowering of erythropoeisis.

Results of studying the local of irritating properties of preparative forms of marsh cinquefoil (Comarum palustre) which were intended for treatment of parasitic of diseases of animals, namely, strongylatosis of gastro-intestinal tract of sheep and calves realized in the conditions of the Republic of Belarus were presented. Preparative forms of Comarum palustre (liquor, tincture, liquid extract and powder) had poorly expressed irritating properties after application into skin of animals and weak irritating action, excluding native forms of tincture and liquid extract on mucous coat eye, that confirms their low toxicity action as a whole on organism of animals.

Development of a new national preparation for the preventive maintenance of cow mastitis, fissures of milking tubes skin of cow udder was realized in the conditions of the Republic of Belarus. The preparation Maz' Solnechnaya ("Unguent Solnechnaya") did not contain antibiotics, hormones and other synthetic components. Natural components of a preparation provide long anti-inflammatory action, stimulate local blood circulation, regeneration of epidermis and accelerate processes of healing of microtraumas. Besides it possesses high efficiency at preventive maintenance of mastitises at cows.

Definition of quality parameters and chemical composition of feeds, evaluation their nutritional value and composing on this basis optimal rations for high productive animals are the most significant conditions for their health and production. More often metabolism disorders registers in the conditions of intensive animal production, at high dairy efficiency and intensive fattening. At animals at disorder of key parameters of technology (unbalanced feeding, hypodynamia, lack of insolation) is broken metabolism, decreases natural resistance, goes down quality of production that conducts to disease, premature culling and to the compelled slaughter of animals. On frequency these diseases occupy on the average 10% from all noncontagious diseases, and on dairy complexes with industrial technology and in specialized feeding economy at intensive cultivation on their share it is necessary over 30% of a noncontagious pathology. Today the control of rations on such indicators, as dry matter level, quantity of exchange energy, the maintenance of a crude and digested protein, amino acids, sugars, starch, cellulose, fat, macro-and microelements, vitamins, and also sugar-energy-protein and calcium-phosphoric parities, acid-base balance has got special value. The lack of those or other nutrients causes infringement of a clinical condition of animals and reduces their efficiency. Among the most widespread diseases of the animals registered in animal industry: cattle ketosis, osteodystrophy, endemic struma, hypomagnesiemia tetany, pasturable tetany, microelementosis, hypovitaminoses A and Е.

Comparative evaluation of the influence of cell-free probiotic preparation Laktimet and cellular probiotic Bifilak on productivity, livability, nonspecific response of suckling piglets in the early extrauterine life was realized in the conditions of the Republic of Belarus.Application of both probiotics increased the productivity of suckling pigs, stimulated the processes of metabolism and natural protection of organism in the early postnatal period in the conditions of specialized pig breeding complexes. Research results showed, that application of brand new cell-free probiotic Laktimet exercised higher influence on suckling pigs. Application of Laktimet made it possibler to increase piglets body weight gain on 7,8%; piglet livability - on 6,7%; and application cellular probiotic preparation Bifilak - on 5,4% and 3,3%, respectively. The same tendency was noted during the analysis of indexes of cellular factors of organism protection. Bactericidal activity of blood serum of experimental animals changed both in connection with age, and under influence of probiotic preparations. During all studied periods the bactericidal activity of blood serum was authentically (P less than 0,05) above in experimental groups in comparison with a control group. At 20-days old piglets there was stated the strengthening of bactericidal activity of blood serum. Throughout all period of experiment the superiority of trial animals over control on indicators of lysozyme activity of blood serum was observed

The diseases of newborn calves with a diarrhea syndrome are the most often registered. Application of the prebiotic preparations Biofon and Biofon-AIL to newborn calves daily with colostrum, milk or water in a dose of 20 ml within 20 days, allows to normalize intestinal digestion of an organism of young growth of calves at the expense of activization of microbiocenosis, stimulates metabolism and nonspecific resistance. Use of prebiotics allows to lower disease of young growth at Biofon application on 20%, Biofon-AIL - on 30% and to increase daily average additional weight gain of calves accordingly on 10,4% and 15,9%. Medical and preventive efficiency of application of prebiotic and probiotic preparations at enteritises at calves reaches 80-90%. Prebiotic preparations Biofon and Biofon-AIL make active nonspecific humoral immunity and exchange processes at newborn calves and can successfully be used for preventive maintenance and therapy of diseases of newborn calves with a diarrhea syndrome | У новорожденных телят наиболее часто регистрируются заболевания с диарейным синдромом. Применение пребиотических препаратов Биофон и Биофон АИЛ новорожденным телятам ежедневно с молозивом, молоком или водой в дозе 20 мл в течение 20 дней, позволяет нормализовать кишечное пищеварение организма молодняка за счет активизации микробиоценоза, стимулируют обмен веществ и неспецифическую резистентность. Использование пребиотиков позволяет снизить заболеваемость молодняка при применении биофона -на 20%, биофона-АИЛ - на 30% и увеличить среднесуточные привесы массы телят соответственно на 10,4% и 15,9%. Лечебная и профилактическая эффективность применения пребиотических и пробиотических препаратов при энтеритах у телят достигает 80-90%. Пребиотики Биофон и Биофон АИЛ активизируют неспецифический гуморальный иммунитет и обменные процессы у новорожденных телят и могут успешно использоваться для профилактики и терапии заболеваний новорожденных телят с диарейным синдромом

In the conditions of the Republic of Belarus there was studied the influence of herbal infusion, tincture, liquid and dry extracts of elecampane (Inula helenium) on morphological and biochemical indexes of pig blood. In course of the study it was established, that preparative forms of elecampane stimulated the formation of blood corpuscle, and also increased of the hemoglobin level in blood of pigs. Administration of elecampane preparations did not cause any authentic changes in blood leukogram of swine; all indicators were within normal limits. Elecampane preparations did not cause changes on the part of biochemical blood indexes of and did not influence the activity of enzymes. Research results showed that herbal infusion, tincture, liquid and dry extracts of elecampane did not render negative influence on swine.

In the conditions of the Republic of Belarus there was studied the antihelmintic characteristics of the preparative forms of marsh cinquefoil (Comarum palustre): herbal infusion, infusion, liquid, extract, pulvis. The research has shown that these preparative forms in the specified dozes had a rather high therapeutic efficiency against strongylatosis of gastro-intestinal tract of young ruminants. The highest therapeutic effect was rendered by a liquid extract of Comarum palustre after its administration to animals in a dose of 0,2 ml/kg twice with 24 hour interval. In this case during the strongylatoses of a gastroenteric tract the antiparasitic intensefficiency of sheep and cattle by the end of experience was 98,1% and 97,3% respectively, and antiparasitic extensefficiency was 90% for both kinds of animals. After herbal infusion application of Comarum palustre for animals (in a dose of 7 ml/kg of live weight before feeding once a day within 3 days continuously) by the end of the 14 day of the experiment made it possible to obtain intensefficiency of 70% for both animal species, and extensefficiency of 60% for sheep and 70% - at calves. Tincture application of marsh cinquefoil for animals in a dose of 1 ml/kg of live weight of twice with 24 hours interval, provided the intensefficiency of 85% for sheep and 84% - for cattle, and extensefficiency of 70% and 80%, respectively. In the conditions of application of a pulvis of marsh cinquefoil in a dose of 500 mg/kg of live weight twice with 24 hours interval, made it possible to obtain the 63,4% intensefficiency for sheep and 67,8% - for calves, and extensive efficiency - 50% and 40%, respectively.