Using macro and microelements, vitamins A and D in correspondence with norms of Institute of Animal Husbandry (1992) per 1 kg of dry substance of a diet: phosphorus - 5,29 g, calcium - 7,46, sodium - 5,59 g, copper - 12,64 mg, zinc - 77,26, magnesium - 77,26, vitamins A and D correspondingly - 23,74 and 1,02 thousand ME for highly productive lactating cows with average daily milk yield of 32 kg at summer feeding compared to Agricultural Academy norms (1985) promotes increase of the so called relative products outcome and profit from basic fatness (3,4%) milk sale per 1 animal at 411 rubles

Research of the reproductive qualities of sows of different genotypes depending on duration of gestation period was realized in the conditions of an industrial pig complex of the Republic of Belarus. In course of research there were analysed 500 sows and 1991 farrowings and was stated that only 61,4% sows had gestation period in the range of physiological standards (at the average -11,5 days). In 17,8% of sows the mentioned above parameter was on 1,6 days shorter and in 1/5 of all sows under investigation it was 0,6 days longer. A higher productive performance was marked in double-breed sows of a genotype (White Large x Belarusian Meaty) with the average gestation period of 114,2 days. There were no essential deviations marked in the duration of the gestation period depending on the ordinal number of farrowing, though for the third farrowing the duration of the gestation period made 114,8 days and was 0,2-0,4 days longer as compared with the first and the second farrowings

Research of possibility of application of sapropel (putrid mud) of the Chervonnoe lake (the Republic of Belarus) in diets of bred and milking sows as one of the ingredients of mixed fodders, as well as the evaluation of its influence of sow development and digestibility of nutritive elements were studied. Application of dry sapropel a source of energy, protein, mineral and vitamin nutritive elements for mixed fodder production rendered the positive influence on sows productive qualities: there was stated the increased number of born piglets on o,5 heads with a higher growing capacity; there was noted the increasing of coefficients of nutritive elements metabolism (crude protein – on 2,7%, crude fat – on 2,9%, free-nitrogen extracts – on 1,3%, and dietary fibre – jn 4,7%) with the simultaneous increasing of nitrogen, calcium, and phosphorous uptake by sows. Nutritional value of the analysed sapropel was 0,23 fodder units and 3,13 MJ of exchange energy per 1 kg of dry matter. Inclusion of 3% sapropel into mixed fodders for pregnant and suckling sows promoted the increasing of quantity of pigs at a birth, body weight of one pig to 3-week age and has ensured young growth with higher energy of growth. Use of sapropel in mixed fodders for sows makes active a metabolism and promotes increase of digestibility of the basic nutrients of a rations

Application of protein, vitamin and mineral supplement in diets of 1-3 months old calves in rate of 5% per weight instead of a part of sunflower cake, containing rape, peas, lupin and vitamid on a basis of halites, phosphite, phosphate, sapropel and a mineral-vitamin preparation in structure of grain forage against winter rations on the basis of rich in herbs hay (5%), milk (68%), mixed fodder (20%), whole grain (7%), and also summer rations with grass and legume mixture (7%), hay (1%), milk (65%), mixed fodder (20%), integral grain (7%) makes it possible to receive daily average weight gain of calves at level 833-867 grams at expenses of forages for 1 centner of weight gain on 3,3-3,4 сentner of forage units. Introduction into rations of the protein, vitamin and mineral supplement on the basis of local protein and mineral raw materials in number of 10% per weight in structure of mixed fodder for calves at the age of 3-6 months old against the background of winter diets with haylage (28%), mixed fodder (64%), molasses (8%), as well as summer diets with grass and legume mixture (30%), mixed fodders (66%), molasses (4%) makes it possible to receive daily average weight gains of calves on 944-967grams at expenses of forages of 4,0-4,1 сentner of forage units. Feeding of 1-6 months old calves with mixed fodders with inclusion of 5-10% of protein, vitamin and mineral supplement per weight with grain high-protein crops against the background of winter and summer diets with a ratio of the deconjugate protein to the non deconjugate one - 65:35 (in control group - 71:29) instead of sunflower cake makes it possible to receive the daily average weight gain at the level of 900-927 grams at expenses of forages 3,7-3,8 сentner per forage unit. Cost of presented mixed fodders decreases on 14%, and the cost price per 1 centner gain - on 7-8%

Results of determination of yielding capacity, chemical composition of initial weight and silage quality of forages prepared from the binary mixtures of Japanese millet (Panicum curs-galli var. frumentaceum), millet (Panicum) and saccharine sorghum (Sorghum saccharatum) realized in the conditions of the Republic of Belarus were presented. Research results showed that the binary mixture of saccharine sorghum with blue lupine (Lupinus angustifolius) in ratio of 70% + 30%, respectively made it possible to obtain the highest efficiency (62,4 t/ha of green material, 15,1 t/ha of dry matter, 13,1 t/ha of fodder units). Mixed sowing of millet, Japanese millet and saccharine sorghum with blue lupine surpassed in productivity the single-crop sowing on 15,5-32,6%. It was established, that the silage produced from the mixture of sorghum and Japanese millet with lupine had higher energy and protein nutritive value: 0,86 and 0,98 fodder unit, respectively; 9,77 and 9,92 mJ of exchange energy per 1 kg of dry matter, respectively; 103, 3 and 108,4 grams of digestible protein per 1 fodder unit. High nutritive value and the best palatability of trial silos promoted the increasing of milk yield on 4,4-5,4% in comparison with the control tests. Haylage which was produced from drought resistant crops had high energy nutritive value: per 1 kg of dry matter there was noted 9,40-9,48 mJ of available energy, 0,89-0,94 fodder units with fodder unit provision with 102-114 grams of digestible protein

The effectiveness of stress prevention with use of sedative remedy Xyla in a complex with preparations Ascorbic acid with glucose, Aesel and Katosal, which improve adaptation, was researched. Application of a complex of neurotropic and adaptogenic preparations before and after dehorning promoted softening of stressful influence, that in turn has positively affected the general condition of animals and intensity of growth. Comparative test of four schemes of preventive maintenance of negative consequences of the stress caused calf dehorning, has shown their high efficiency. However more expressed stimulating influence on intensity of metabolism, antioxidant status, natural resistance, adaptation to action of stresses-factors and rates of a body weight gain were rendered by the scheme with use of preparations Aesel, Ascorbic acid with glucose and Ksila

There was studied the width of distribution and peculiarity of clinical manifestation of mineral exchange diseases at pregnant sows, and also perfection of preventive actions at pathology of mineral metabolism in the conditions of prophylactic medical examination. Results of research have shown, that diseases of mineral metabolism widespread (84,7%) among pregnant sows in the conditions of industrial production, are most extended scarce conditions on Zn (17,7%) and Fe (22,5%). Clinically this insufficiency was expressed by oppression, appetite distortion, occurrence on a skin of specifically red stains correct roundish the form: with the clarified sites in the centre, are registered as abortions at final stages of pregnancy. It is established, that the way of preventive maintenance of hypomicroelementosis of pregnant sows with use of chelated forms of microelements is more preferable than sows, as reduces percent of clinical display of Zn and Fe deficiency, stabilize level of hematological and biochemical indicators of blood more effectively, and also raise industrial indicators of pregnant sows. | Целью работы было изучение широты распространения и особенностей клинического проявления заболеваний минерального обмена у супоросных свиноматок, а также совершенствование профилактических мероприятий при патологии минерального обмена веществ в условиях диспансеризации. Результаты исследований показали, что болезни минерального обмена веществ широко распространены (84,7%) среди супоросных свино¬маток в условиях промышленного производства, наиболее распространены дефицитные состояния по Zn (17,7%) и Fe (22,5%). Клинически эта сочетанная недостаточность выражалась угнетением, залеживанием, понижением и извращением аппетита, появлением на коже специфически красных пятен правильной округлой форма: с просветленными участками в центре, зарегистрированы так же аборты на конечных стадиях супоросности. Установлено, что способ профилактики гипомикроэлементозов супоросных свиноматок с использованием хелатных форм микроэлементов предпочтительнее, поскольку сокращает процент клинического проявления дефицита цинка и железа, эффективнее стабилизируют уровень гематологических и биохимических показателей крови, а также повышают производственные показатели супоросных свиноматок.

Despite of presence of a wide choice of antihelminthics, in the Republic of Belarus it is still a real problem of development of preparations that provide long-term treatment and preventive maintenance efficiency against helminthosis. At the same time, helminthes and anthelminthics render the immunosuppression action. The solution of this problem can be a combined application of antihelminthics and adjuvants. There were proposed preparations Albepolis and Averpolis. Their application made it possible not only to release an organism of animals from parasites, but also to correct the state of immune system. The obtained research data confirm the available data about the immunosuppression action of parasites on an organism of animals. There was also is noted the immunosuppression action of Albendazol and Aversektin C in therapeutic doses. Albendazol possess a wide spectrum of action against trematodes, nematodes, cestodes. It interrupts the metabolism, oppresses fumarate reductase activity and adenosine triphosphate synthesis of a parasite. It proved to be low-toxic for homoiothermal animals. Albendazol rendered positove influence on growth, development and increase of cattle productivity.

In the conditions of the Republic of Belarus there was studied the antihelmintic characteristics of the preparative forms of marsh cinquefoil (Comarum palustre): herbal infusion, infusion, liquid, extract, pulvis. The research has shown that these preparative forms in the specified dozes had a rather high therapeutic efficiency against strongylatosis of gastro-intestinal tract of young ruminants. The highest therapeutic effect was rendered by a liquid extract of Comarum palustre after its administration to animals in a dose of 0,2 ml/kg twice with 24 hour interval. In this case during the strongylatoses of a gastroenteric tract the antiparasitic intensefficiency of sheep and cattle by the end of experience was 98,1% and 97,3% respectively, and antiparasitic extensefficiency was 90% for both kinds of animals. After herbal infusion application of Comarum palustre for animals (in a dose of 7 ml/kg of live weight before feeding once a day within 3 days continuously) by the end of the 14 day of the experiment made it possible to obtain intensefficiency of 70% for both animal species, and extensefficiency of 60% for sheep and 70% - at calves. Tincture application of marsh cinquefoil for animals in a dose of 1 ml/kg of live weight of twice with 24 hours interval, provided the intensefficiency of 85% for sheep and 84% - for cattle, and extensefficiency of 70% and 80%, respectively. In the conditions of application of a pulvis of marsh cinquefoil in a dose of 500 mg/kg of live weight twice with 24 hours interval, made it possible to obtain the 63,4% intensefficiency for sheep and 67,8% - for calves, and extensive efficiency - 50% and 40%, respectively.

In the conditions of the Republic of Belarus there was realized an experimental study of a new method treatment of calves diseased with abomasoenteritis by means of application of a preparation Ranitidin. As a result of realized research it was established that the preparation had an expressed therapeutic activity. Inclusion of Ranitidin preparation into the complex therapeutic regimen of calves sick with abomasoenteritis with the enteral feeding once in day in a dose of 0,15 g promoted the reduction of duration and decrease in severity of the disease. There were presented the results of biochemical blood indicators in trial and control groups of calves, haematologic indices in trial and control groups of calves prior to the beginning of experiment and in the end of the test.