In Peninsular Malaysia, footand-mouth disease (FMD) has been reported since early 1860 which then became sporadic, causing outbreaks every year. Since then, Peninsular Malaysia has become endemic with FMD. The aim of this study is to provide findings of the current FMD occurrence and its serotyping in Peninsular Malaysia. An identification of Foot and Mouth Disease serotype was carried out in Peninsular Malaysia by the Regional Veterinary Laboratory Kota Bharu (RVLKB) only. Epithelial tissue samples were received from 10 states throughout Peninsular Malaysia from 2012 until 2016. Indirect sandwich ELISA was performed using ELISA kit for FMDV antigen detection supplied from the Institute for Animal Health, Pirbright Laboratory. All findings and results in this paper were based on samples received by RVLKB and does not reflect overall cases reported to State DVS or to DVS Malaysia. From the results, 2013 had the highest samples positive for FMDV (35% from 43 samples), followed by 2014 (31% from 80 samples), 2012 (24% from 122 samples), 2015 (21% from 39 samples) and the lowest is 2016 (17% from 194 samples). The FMDV serotypes detected throughout 2012 to 2016 from 110 positive samples were Serotype O (80%), followed by Serotype A (20%) and none from Serotype Asia 1. Strict regulation, FMD vaccine evaluation by LPB ELISA and strict animal movement shall be considered to achieve FMD free for upcoming Year 2020.

Phylogeography data are of paramount importance in studying the molecular epidemiology dynamics of foot-and-mouth disease virus (FMDV). In this study, epithelial samples and oesophageal-pharyngeal fluids were collected from 361 convalescent animals (cattle and buffaloes) in the field throughout Tanzania between 2009 and 2013. The single plex real-time RT-PCR (qRT-PCR) assay for rapid and accurate diagnosis of FMDV employing the Callahan 3DF-2, 3DF-R primers and Callahan 3DP-1 probe were used. Preparation of the samples was performed according to the OIE manual, with a Kenya O serotype obtained from the attenuated vaccine serving as a positive control and samples collected from healthy animals serving as true negatives. The results indicated that 53.49% of samples (n = 176) were positive for FMDV genome by qRT-PCR, with Ct values ranging from 14 to 32. In addition, molecular typing of the FMDV genome positive samples using serotype specific primers revealed the existence of several serotypes: serotype South Africa Territory 1 (SAT1) (34.25%, n = 60), serotype A (68.92%, n = 98), serotype O (59.20%, n = 98) and SAT2 (54.54%, n = 96). The virus protein 1 sequences analysis for 35 samples was performed and the collective results indicated: 54.28% serotype O, 25.71% serotype A, 14.28% serotype SAT1 and 2.85% serotype SAT2. Therefore in this study, both the phylogenetic trees and spatial distribution of serotypes elucidated the phylodynamics of multiple FMDV field strains in Tanzania and neighbouring countries.

Eco-tourism depending on wildlife is becoming increasingly profitable and landowners are beginning to favor game farming and ecotourism. In these areas, large-scale translocation of wildlife involves a diversity of species and large populations. The African buffalo (Syncerus caffer) is one of the major tourist attractions in Zambia. It accounts for 8.7% and 12.4% of the total animal species hunted in the Game Management Areas and the total hunting revenue earned in Zambia, respectively. It is ecologically an important animal species essential for the purpose of habitat control and facilitating the provision of suitable grazing pastures. However, the rearing of the African buffalo on game ranches has been hampered by its carrier state of the Southern Africa Terroritory (SAT) serotypes of foot and mouth disease virus (FMD). The African buffalo is also known to be a carrier of Theileria parva lawrencei, the causative agent of corridor disease (CD) that continues to have devastating effects on the livestock industry in Zambia. In addition, the importation of buffaloes from countries with populations endemic to bovine tuberculosis is highly restricted. Veterinary regulations in Zambia, strongly advocate against the translocation of buffaloes from protected areas to private ranches for disease control purposes thereby mounting a considerable constraint on the economic and ecological viability of the industry. It is hoped that this review will motivate the relevant government authorities in exploiting ways in which this animal species play a central role in eco-tourism.

Objective: This study aimed to evaluate the effects of feed supplementation on the body condition of cows suffering from foot and mouth disease (FMD) and the birth weight of their calves. Materials and Methods: The study involved 30 pregnant cows (6–7 months gestation), divided into five groups of six cows each. Groups A, B, C, D, and group E were supplemented with concentrates at levels of 0%, 0.2%, 0.4%, 0.6%, and 0.8% of body weight, respectively. The concentrates comprised cassava peels (60%), corn mill (40%), urea (3% of total feed needed), and minerals (25% of total feed needed). Variables: Following the onset of FMD symptoms, observations were made on the duration of hypersalivation, nasal discharge, snout and nose erosion, tongue and lip erosion, foot swelling, refusal to eat, and return to normal feed consumption. Results: The results showed that feed supplementation accelerated recovery such as time from hypersalivation, nasal discharge, muzzle erosion, and tongue (p < 0.05). However, no significant difference in interdigital wounds and duration of reluctance to eat due to FMD. Providing nutri¬ent-rich feed also increases the body condition scores after FMD infection and the calf birth weight (p < 0.05) of Bali cattle. Conclusion: It was concluded that nutrient-rich feed supplementation accelerates cow recovery from FMD, maintains body condition, and increases the calf birth weight of Bali cattle. [J Adv Vet Anim Res 2025; 12(1.000): 106-116]