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Comparison of speed of onset and analgesic effect of 2% mepivacaine hydrochloride deposited within or outside the neurovascular bundle at the level of the proximal sesamoid bones in horses with naturally occurring forefoot-related lameness
2020
Schumacher, John | Cole, Robert C. | DeGraves, Fred J. | Cofield, Lawrence G.
OBJECTIVE To compare the speed of onset and analgesic effect of mepivacaine deposited within or immediately outside the neurovascular bundle at the base of the proximal sesamoid bones in horses. ANIMALS 6 horses with naturally occurring forefoot-related lameness. PROCEDURES In a crossover study design, horses were randomly assigned to receive 1 of 2 treatments first, with the second treatment administered 3 to 7 days later. Trotting gait was analyzed with an inertial sensor–based motion analysis system immediately before treatment to determine degree of lameness. Afterward, ultrasound guidance was used to inject 2% mepivacaine hydrochloride around the palmar digital nerves of the affected forelimb at the level of the base of the proximal sesamoid bones either within the subcircumneural space or outside the circumneural sheath. After injection, gait was reevaluated at 5-minute intervals for 45 minutes. RESULTS Mepivacaine deposition outside the circumneural sheath did not resolve lameness in any horse; for 3 horses, the mean time to 70% reduction of initial vertical head movement was 13.3 minutes, and the remaining 3 horses had no such reduction at any point. Mepivacaine deposition within the subcircumneural space resulted in a mean time to 70% reduction of initial vertical head movement of 6.7 minutes and mean time to resolution of lameness of 21.7 minutes. CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that when peripheral nerves of horses lie within a sheath, local anesthetic solution should be deposited within the sheath for an effective nerve block. If local anesthetic solution is deposited outside the sheath, the nerve block may yield erroneous results.
显示更多 [+] 显示较少 [-]Effects of kernel and window setting combinations on assessments of small and complicated vasculature in computed tomography angiographic images of dogs with and without tumors
2020
Yoon, Sooa A. | Park, Seungjo J. | Choi, Jihye H.
OBJECTIVE To evaluate the effect of kernel and window settings on the assessment of small and complicated vasculature in CT angiographic (CTA) images of kidneys, jejunum with mesentery, and tumors in dogs. ANIMALS 20 healthy dogs and 20 dogs with tumors. PROCEDURES Images from CTA performed previously in dogs were reconstructed with 3 different combinations of kernel and window settings (soft kernel with soft tissue window, soft kernel with bone window, and sharp kernel with bone window), and reconstructed images of the left kidney and the jejunum with the mesentery in healthy dogs and tumors in affected dogs were evaluated by reviewers blinded to the settings. RESULTS For images of kidney and jejunum with mesentery, reviewers’ scores for the conspicuity of vascularity in the arterial phase and the differentiation of the organs from the adjacent structures were significantly higher when viewed in bone window (vs soft tissue window) regardless of kernel setting. For images of head and gastrointestinal tumors, reviewers’ scores for differentiation of intratumoral vasculature were higher when viewed in sharp kernel with bone window versus other setting combinations. However, the conspicuity of gastrointestinal, hepatic, or splenic tumoral vessels from the adjacent structures had higher reviewer scores for images in soft kernel with soft tissue window, compared with other setting combinations. CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that reconstruction of CTA images with sharp kernel combined with bone window settings might have clinical utility in evaluating and planning treatments for dogs with various tumors; however, additional research is warranted to further identify effects of various kernel and window setting combinations on assessments of small and complicated vasculature in larger and more diverse populations of dogs with and without tumors.
显示更多 [+] 显示较少 [-]Evaluation of a multipump air pistol as a method for euthanizing young dairy goat kids
2020
Hempstead, Melissa N. | Fowler, Jennifer L. | Shearer, Jane K. | Plummer, Paul J.
OBJECTIVE To assess the extent of damage to the skull and brain of cadaveric dairy goat kids caused by a .22-caliber, 16-g pellet fired from a multipump air pistol at various power levels. SAMPLE Cadavers of 8 male and 7 female dairy goat kids ≤ 5 days old. PROCEDURES Each cadaver was positioned in sternal recumbency with the head and neck extended on a straw bale. A multipump air pistol was held with the barrel perpendicular to and 2.5 cm from the head at the intersection of 2 imaginary lines that extended from the lateral canthus of each eye to the middle of the contralateral ear base and fired at half (5 pumps; n = 2), intermediate (7 pumps; 2), or full (10 pumps; 11) power. The head and neck were removed from the carcass for CT imaging and gross sectioning to determine the location of the pellet and extent of damage caused to the skull and brain. RESULTS The pellet successfully penetrated the skull of all 13 heads shot at full or intermediate power and 1 of the 2 heads shot at half power. The pellet did not fragment after entering the skull of any cadaver and penetrated the brainstem (necessary for instantaneous death) in only 7 cadavers. CONCLUSIONS AND CLINICAL RELEVANCE The described technique was insufficient for use as a stand-alone method for euthanizing young dairy goat kids. Modification of the technique warrants further research to determine whether air pistols can be used to effectively euthanize young goat kids.
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