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Pathological description and immunohistochemical demonstration of ovine abortion associated with Toxoplasma gondii in Iran
2013
Rassouli, M., Ferdowsi University of Mashhad, Mashhad 9177948974, Iran | Razmi, G.R., Ferdowsi University of Mashhad, Mashhad 9177948974, Iran | Movassaghi, A.R., Ferdowsi University of Mashhad, Mashhad 9177948974, Iran | Bassami, M.R., Ferdowsi University of Mashhad, Mashhad 9177948974, Iran | Sami, M., Ferdowsi University of Mashhad, Mashhad 9177948974, Iran
The obligatory intracellular protozoan parasite Toxoplasma gondii is a major world wide cause of infectious ovine abortion. In some different diagnostic techniques that are being used to detect this pathogen in ovine fetuses, immunohistochemistry (IHC) is a very sensitive and expensive one. Histopathology is not truly a specific and sensitive test for Toxoplasma infection but it can be helpful to choose some suspected tissues for IHC. In this study 9.5% of 200 samples (aborted ovine fetuses internal organs such as brain, liver, heart, lung, kidney, spleen) (4.6~14.4% with 95% CI) were positive in IHC with a very good logical agreement among different diagnostic techniques (κ = 0.73, 0.8) and with no significant difference among different fetal age groups (p 0.05).
显示更多 [+] 显示较少 [-]Diagnostic imaging of isolated splenic torsion in two dogs
2007
Choi, J.H. (Haemaru Referral Animal Hospital, Seongnam, Republic of Korea) | Kim, H.W. (Haemaru Referral Animal Hospital, Seongnam, Republic of Korea) | Kim, J.K. (Haemaru Referral Animal Hospital, Seongnam, Republic of Korea) | Jang, J.Y. (Haemaru Referral Animal Hospital, Seongnam, Republic of Korea) | Kim, J.Y. (Seoul National University, Seoul, Republic of Korea) | Yoon, J.H. (Seoul National University, Seoul, Republic of Korea), E-mail: heeyoon@snu.ac.kr
Isolated splenic torsion is a rare disease, which is usually produced in deep-chest large breed dogs. A five-year old Pitbull terrier and a four-year old Yorkshire terrier were diagnosed as isolated splenic torsion with chronic form. Leukocytosis, anemia and elevated hepatic enzyme level were found in blood test and a large amount of ascites was observed. Abdominal radiography revealed splenomegaly and ascites and ultrasonography showed diffuse hypoechoic change of spleen in case 1 and hyperechoic change of spleen with focal hypoechoic regions in case 2, thromboembolism of splenic vein and abnormal direction of spleen.
显示更多 [+] 显示较少 [-]Histopathological effects of the nematode Amidostomum acutum on the small intestines of two aquatic birds: Fulica atra and Gallinula chloropus
2021
Altaif, K.I. | Mhaisen, F.T. | Mizhir, A.H.
The small intestine of two rallid aquatic birds (Fulica atra Linnaeus, 1758 and Gallinula chloropus (Linnaeus, 1758) from Bahr Al-Najaf depression, southwest of Al-Najaf city, mid-Iraq), were infected with the nematode Amidostomum acutum Seurat, 1918 with a prevalence of 25% and 50%, respectively, and a mean intensity of 24.5 and 30, respectively. The infected birds showed several gross pathological and microscopic lesions in their small intestine due to the infection with this nematode. The gross lesions included hypertrophy in the anterior part of the duodenum and small rough nodules on the small intestine wall. Microscopic lesions included necrosis and shortening of villi with their fullness with inflammatory cells, degeneration of villi, and an increased number of acini at the base of the intestinal villi.
显示更多 [+] 显示较少 [-]A case of elk (Cervus elaphus) coccidiosis in Korea
2010
Yoon, S.S., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Bae, Y.C., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Byun, J.W., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Lee, K.H., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Jang, H., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Song, J.Y., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea | Wee, S.H., National Veterinary Research and Quarantine Service, Anyang, Republic of Korea
A thirty-five week old elk was referred for Chronic Wasting Disease (CWD) confirmation from Chungnam province in Korea. Necropsy revealed much bloody contents in the lumen of small and large intestines, and reddening of its mucosa. Microscopically, few coccidia showing various developmental stages were infiltrated in lamina propria of small intestine with granulomatous inflammation and congestion. They were identified as Eimeria spp. according to their location and morphological characteristics. Because fecal examination and oocyst culture were not available, the species of the Eimeria could not be confirmed. There were no detection of pathogenic bacteria such as clostridia and virus in intestinal contents. CWD was shown to be negative in immunohistochemistry test. In conclusion, it was the first Eimeria case detected in small intestine of Korean domestic elk as far as we know although Eimeria spp. were not the main cause of death.
显示更多 [+] 显示较少 [-]Time-course response of epichlorohydrin on epididymal histopathology in rats
2009
Kim, K.H., Chonnam National University, Gwangju, Republic of Korea | Shin, I.S., Chonnam National University, Gwangju, Republic of Korea | Lim, J.H., Chonnam National University, Gwangju, Republic of Korea | Kim, S.H., Chonnam National University, Gwangju, Republic of Korea | Park, N.H., Chonnam National University, Gwangju, Republic of Korea | Moon, C.J., Chonnam National University, Gwangju, Republic of Korea | Kim, S.H., Chonnam National University, Gwangju, Republic of Korea | Shin, D.H., Chonnam National University, Gwangju, Republic of Korea | Kim, J.C., Chonnam National University, Gwangju, Republic of Korea
This research aimed to investigate the time-course effect of epichlorohydrin (ECH) on epididymal histopathology in Sprague-Dawley rats. Twenty-four male rats were randomly assigned to four groups with 6 rats in each group and were administered a single oral dose of ECH (70 mg/kg) or its vehicle. Six animals each were sacrificed on days 0 (control), 1, 2, and 7 after treatment. During the study period, clinical signs, body weights, reproductive organ weights, testicular spermatid count, epididymal sperm count, motility and morphology, and histopathology were examined. No treatment-related effects on body weights and reproductive organ weights were noted at any time point. On the contrary, sperm motility decreased slightly on days 1 and 2 after treatment and then decreased significantly on day 7 after treatment. The first signs of histological changes were the appearance of cell debris in the ducts and vacuolization of the epithelial cells observed in the proximal caput epididymis on day 1 after treatment. The incidences and grades of the histological changes including cell debris in the ducts, epithelial vacuolization, oligospermia, and epithelial disruption increased on day 2 and then decreased slightly on day 7 after treatment. These results show that a single oral dose of 70 mg/kg ECH to male rats results in cell debris in the ducts and vacuolization of the epithelial cells in the proximal caput epididymis, followed by reversible oligospermia, epithelial disruption, and decreased sperm motility.
显示更多 [+] 显示较少 [-]Primary intestinal mast cell tumor in a Russian Blue cat: ultrasonographic and histopathological findings
2017
Kim, S.J., Bom animal hospital, Seoul, Republic of Korea | Jaekal, J., Bom animal hospital, Seoul, Republic of Korea | Kim, J.Y., Bom animal hospital, Seoul, Republic of Korea | Oh, D.K., Bom animal hospital, Seoul, Republic of Korea | Cho, J.H., Bom animal hospital, Seoul, Republic of Korea | Kang, M.H., Konkuk University, Seoul, Republic of Korea | Park, H.M., Konkuk University, Seoul, Republic of Korea
A 11-year-old, female Russian Blue cat was presented with anorexia, vomiting, and diarrhea lasting for 3 days. Abdominal ultrasonography revealed a hypoechoic, non-circumferential, and eccentrically formed intestinal loop with altered wall layering and thickening of the tunica muscularis. After surgical resection, histopathologic examination confirmed an infiltrative, round-cell neoplasm composed of sheets and cords of neoplastic mast cells within a fibrotic, edematous stroma. The cat was alive and healthy 6 months after surgery. To the best of our knowledge, this is the first reported case of an intestinal mast cell tumor in a Russian Blue cat in South Korea.
显示更多 [+] 显示较少 [-]Acute and subacute toxicity of trichlorfon in guppies (Poecilia reticulata)
2009
Heo, G.J., Chungbuk National University, Cheongju, Republic of Korea | Shin, G.W., Chonbuk National University, Jeonju, Republic of Korea
The aim of the present study was to determine the acute and subacute potential of trichlorfon in guppies (Poecilia reticulata). We first defined the 24h median tolerance limit (TLm∧24h) of the fish to trichlorfon. Guppies were then treated with TLm∧24h and 1/10 TLm∧24h trichlorfon concentrations to evaluate of any histological alterations occurred. The TLm∧24h value of trichlorfon was 11 ppm. This concentration resulted in acute toxicity to the gills and kidneys with edema, hyperplasia of the gill lamellae, and vacuolated degeneration and necrosis of renal tubular cells. In the case of subacute toxicity using a 10-fold dilution of the TLm∧24h value (1.1 ppm), no behavioral changes, external lesions or histopathological changes were observed. Therefore, safe concentration of trichlorfon might be 1.1 ppm in guppy for controlling parasitic infections.
显示更多 [+] 显示较少 [-]Electrocution caused by a fallen electric wire in Korean native cattles
2008
Bae, Y.C. (National Veterinary Research and Quarantine Service, Anyang, Republic of Korea), E-mail: baeyc@nvrqs.go.kr | Lee, K.H. (National Veterinary Research and Quarantine Service, Anyang, Republic of Korea) | Yoon, S.S. (National Veterinary Research and Quarantine Service, Anyang, Republic of Korea) | Heo, J.H. (Gyeongnam Livestock Promotion Institute South-branch, Tongyoung, Republic of Korea) | Lee, O.S. (National Veterinary Research and Quarantine Service, Anyang, Republic of Korea)
We report the electrocution of Korean native cattle by a fallen electric wire, which caused the death of thirteen animals. The owner of the cattle felt an electric shock on touching the steel pen and found a fallen 220-V wire on the roof of the barn; additionally, the roof was singed. Clinically, the animals developed spasm, difficulty breathing, and excessive salivation. Histopathologically, many visceral organs revealed severe congestion or hemorrhage, which is consistent with previous reports. This study revealed that the proper installation of electric wires on farms is essential to prevent economic loss by electrocution.
显示更多 [+] 显示较少 [-]Toxicological effects of perfluorooctanoic acid in rats
2008
Kim, Y.H. (Chungnam National University, Daejeon, Republic of Korea) | Cho, E.S. (Chungnam National University, Daejeon, Republic of Korea) | Kim, A.Y. (Chungnam National University, Daejeon, Republic of Korea) | Kim, S.H. (Chungnam National University, Daejeon, Republic of Korea) | Park, M.S. (Chungnam National University, Daejeon, Republic of Korea) | Cho, S.W. (Chungnam National University, Daejeon, Republic of Korea) | Ryu, S.Y. (Chungnam National University, Daejeon, Republic of Korea) | Jung, J.Y. (Chungnam National University, Daejeon, Republic of Korea) | Son, H.Y. (Chungnam National University, Daejeon, Republic of Korea), E-mail: hyson@cnu.ac.kr
Perfluorooctanoic acid (PFOA), a member of the perfluoroalkyl acids that have wide commercial applications, is persistent organic pollutants widely spread throughout the environment and human population. But little is known about the adverse biological effects of the PFOA. In the present study, the toxicological effects of PFOA were investigated in rats. Sprague-Dawley rats (N = 10 in each group) were orally administered with PFOA in drinking water for 4 weeks (0, 100, 200, or 400 ppm in male, and 0, 200, 400, or 800 ppm in female). These female rats given 800 ppm died during the study. PFOA treatment decreased the body weight gain and increased the liver weights in both genders. Serum biochemical investigations revealed significant increases in the aspartate aminotransferase, alanine transaminase, alkaline phosphatase, blood urea nitrogen, total cholesterol, and total bilirubin in male but in female. Serum estradiol (E2) levels were increased in all treated in all treated rats. Histopathologically, hepatocellular hypertrophy around central vein was noted in the liver of treated rats. No significant histopathological change were noted in other organs. In conclusion, PFOA induced toxicological changes in the liver and increased serum E2 level which was not related to histopathological changes of endocrine and reproductive system.
显示更多 [+] 显示较少 [-]Epidemiological studies on the respiratory cryptosporidiosis of broiler in Korea
1993
Oh, M.H. | Eun, G.S. | Kim, H.J. | Chung, U.I. (Miwon Institute of Animal Science, Seoul (Korea Republic))