A 3-year-old, intact female, Shih-tzu dog was presented with a 15-day history of vomiting, depression, and anorexia. On physical examination, systolic ejection murmurs with precordial thrill at the left heart base were detected. A diagnosis of congenital pulmonic stenosis (PS) was made mainly from the thoracic radiography, electrocardiography, and echocardiography. On complete blood counts and serum biochemistry profiles, the dog had already chronic renal failure (CRF). Thoracic radiography confirmed that main pulmonary artery was tremendously buldged and electrocardiography was suggestive of severe right ventricular hypertrophy.

A 6-month-old intact male Maltese dog (2.5 kg of body weight) was presented with the primary complaint of heart murmur and exercise intolerance. Diagnostic studies revealed severe pulmonic stenosis. Since the pressure gradient in stenotic pulmonic valve area was higher than 200 mmHg (maximum flow velocity = 7.1 m/s), the dog was underwent ballon valvuloplasty. With this procedure, the peak pulmonic velocity was reduced to 3.0 m/s (PG = 36 mmHg). Periodic re-evaluations performed in monthly interval revealed no further deterioration even after 4 month of procedure.

Isolated splenic torsion is a rare disease, which is usually produced in deep-chest large breed dogs. A five-year old Pitbull terrier and a four-year old Yorkshire terrier were diagnosed as isolated splenic torsion with chronic form. Leukocytosis, anemia and elevated hepatic enzyme level were found in blood test and a large amount of ascites was observed. Abdominal radiography revealed splenomegaly and ascites and ultrasonography showed diffuse hypoechoic change of spleen in case 1 and hyperechoic change of spleen with focal hypoechoic regions in case 2, thromboembolism of splenic vein and abnormal direction of spleen.

The objective of the study was to establish routine parentage testing system in Beagle dogs using 22 ISAG (International Society for Animal Genetics) canine microsatellite markers (2005). Blood collections were obtained from a mother dog, 4 candidate father dogs and 3 offspring (n = 8). Genomic DNA samples were extracted from 8 Beagle dogs blood for PCR analysis. PCR products for the allele were analyzed by ABI 3130 DNA Sequencer and GeneScan (Ver 3.0) analysis and Genotyper (Ver. 2.1) software.

A 6-year-old female Maltese dog (body weight 2.0 kg) was referred to the Veterinary Teaching Hospital. Kangwon National University with primary complaints including exercise intolerance and heart murmur. Based on clinical and diagnostic findings including grade V/VI left basal continuous murmur, bounding femoral pulsation, left ventricular enlargement pattern in electrocardiogram, cardiomegaly with aortic bulging on the thoracic radiography, and shunt flow between aorta and pulmonary artery on the echocardiography, the dog was diagnosed as the left-to-right patent ductus arteriosus.

Cutaneous asthenia or dematosparaxis is an uncommon, congenital and inherited connective tissue disease of dog and cat, resembling Ehlers-Danlos syndrome (EDS) in man. EDS is characterized by loose, hyperextensible and, fragile skin, it is attributed to mutations in connective tissue gene. These mutations cause defects in type Ⅰ or Ⅲ collagen synthesis and as a result lack of strength or elasticity to skin, joint, ligament and vessels. EDS-affected animals often experience subcutaneous hematomas that have long bleeding times.

In 3 dogs with gallbladder mucocele, rupture of gallbladder was diagnosed and treated. Although the diagnosis of gallbladder is challenging due to non-specific clinical signs and physical examination findings, mucoceles are ultrasonographically characterized by the appearance of the stellate of finely striated bile patterns and differ from biliary sludge by the absence of gravity dependent bile movement. In this case, gallbladder rupture caused by mucocele can be diagnosed based on not only above characteristics but secondary lesion such as ascites around gallbladder and swollen hyperechoic mesentery.

A-7-year-old, intact female Korean Jindo dog was referred due to ataxia and pain on palpation of the thorax. Radiograph, echocardiography and computed tomogram revealed a mass on the heart base region and osteolytic change of fifth thoracic (T5) vertebra. At necropsy, a firm, encapsulated and round mass was seen arising from the heart base region surrounding the ascending aorta and pulmonary artery. Histopathologically, nests of cuboidal and polyhedral cells having abundantly granular and eosinophilic cytoplasm with round to oval nucleus were separated by fibrous septa.

A two-year-old intact male Miniature Schnauzer was presented with signs of anorexia and abdominal pain with six-week duration. An exploratory ventral midline laparotomy was performed for a confirmative diagnostic and therapeutic purpose, and the presence of a string gastrointestinal linear foreign body was observed originating in the stomach, extending to the ileum. In the small intestine, the linear foreign body was located in the serosal layer. A partial enterotomy was performed on the mesenteric border of the intestine and the string was removed.

An intact male, 3-month-old, Great Pyrenees mountain dog, weighing 7.3 kg with a history of severe hematuria during 2 months was referred. Hematology showed mild leukocytosis. There were no remarkable findings in abdominal radiographs due to ingesta and gas in the gastrointestinal tracts. Ultrasonographs showed bilateral hydronephrosis, bilateral dilated and tortuous ureters, and hyperechoic sludges in the urinary bladder (UB). And a dilated cavity was identified cranial to the UB. Excretory urography and cystography were performed to examine the cause of hydronephrosis and an abnormal cavity cranial to the UB.