The canines affected with skin affections were subjected to blood biochemical profile assay. The affections included dermatitis, sarcoptic mange, demodectic mange, eczema, flea allergy dermatitis, skin allergy and bacterial dermatitis. The blood profile of serum iron, triglyceride, cholesterol, uric acid, urea, creatinine, lactate dehydrogenase, and gamma glutamyl transpeptidase were compared with the blood of healthy dogs. The serum iron, urea and creatinine were comparable in both the groups. It was concluded that stress of dermatosis reflected in enzyme (higher in GGT) and lipid profile (higher in triglyceride, cholesterol) of patients, while renal parameters (urea and creatinine) remain unaffected on account of skin ailments.

The study evaluated in-vitro antibacterial activity of seabuckthorn (Hippophae rhamnoides L.)leaves using disc diffusion method against common skin and wound pathogens. Methanolic hot and cold extracts of green seabuckthorn leaves were tested against 160 microbial isolates obtained from clinical skin and wound infection cases of different animal species. Different concentrations of leaf extracts i.e. 0.5%, 2%, 3%, 4% and 5% were tested against 1×108 cfu/ml bacteria inoculated on Mueller-Hinton agar (MHA). The inhibitory effect of SBT leaf extract at 5% concentration was observed to be almost 50% as compared to the standard drugs used as positive control against isolate.