Clinical examination of 380 rearing sheep revealed that 30 animal were suffering from skin abscesses with an incidence of (7.89%). Bacteriological examination of 30 swabs from affected sheep revealed isolation of 30 isolates of C. pseudotuberculosis (48.39%) , 18 isolates of S. aureus (29.03%) and 14 isolates of S. aureus subsp. anaerobius (22.58).The isolated bacteria were identified morphologically and biochemically.The results of animal pathogenicity test showed that C. pseudotuberculosis isolates were 100% pathogenic to guinea pigs and 80% of S.aureus isolates were pathogenic to mice, while all isolates of S. aureus subsp. anaerobius were pathogenic to mice. The dead animals showed haemorrhage and symptoms of septicaemia, C. pseudotuberculosis, S.aureus and S. aureus subsp. anaerobius were reisolated from the dead animals. Antimicrobial sensitivity of C. pseudotuberculosis , S. aureus and S. aureus subsp. anaerobius isolates to some antimicrobial agents which usually used in farms showed that from 90% to 100% of C. pseudotuberculosis isolates were sensitive to erythromycin, amoxicillin, tetracycline ,streptomycin, ampicillin and rifampicin while S. aureus isolates (from 55% to 66%) were sensitive to rifampicin,tetracycline ,erythromycin and streptomycin, while S. aureus subsp. anaerobius isolates were moderately resistant to all used antimicrobial agents.

Therapeutic and anti-inflammatory potential of aqueous extract of Phyllanthus emblica (Common name - Amla) was evaluated in mastitic cows. The milk Somatic Cell Count (SCC) and ceruloplasmin concentration was significantly (P0.05) higher in mastitic cows prior to treatment. The parameters of mastitic cows treated with P. emblica (group III) and with amoxicillin sulbactum combination (group IV) were compared to that of healthy cows (group I and II). Significant reduction (P0.05) in Somatic Cell Count (SCC) was observed in both the treated groups. The level of ceruloplasmin significantly (P0.05) reduced in group III and IV after treatment. Results of the present experiment indicate reduction of SCC and ceruloplasmin level in the mastitic animals treated with the P.emblica extract. The extract of P. emblica significantly reduced (P0.05) the udder inflammation and helped in lowering the concentration of inflammatory marker ceruloplasmin. Therefore P. emblica extract could be advised for the treatment of bovine mastitis.

Therapeutic and anti-oxidant potential of vitamin E and selenium was evaluated in mastitic cows. The CMT point score and milk somatic cell count (SCC) was significantly (P0.05) higher in mastitic cows prior to treatment. Reduced activity of enzymatic anti-oxidant catalase was observed in mastitic animals. The parameters studied in mastitic cows treated amoxicillin sulbactum (group II) and with amoxicillin sulbactum, vitamin E and selenium (group III) were compared with that of group I healthy cows. Significant reduction (P0.05) in CMT and SCC was observed in both the treated groups. However, reduction in CMT point score and SCC was more pronounced in group III than group II cows. Synergistic action of antibiotic and vitamin E selenium significantly (P0.05) enhanced the activity of catalase in group III mastitic animals on day 8 time period. Therefore, vitamin E and selenium supplementation could be advised in the therapy of mastitis.