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Preliminary efficacy trial of cymelarsan in mice artificially infected with Trypanosoma brucei brucei isolated from a dog in Zambia
1995
Syakalima, M. (Hokkaido Univ., Sapporo (Japan)) | Yasuda, J. | Hashimoto, A.
An efficacy trial of Cymelarsan (R) on a Zambian strain of Trypanosoma brucei brucei was done. Twenty-five male mice were infected intraperitoneally with 10(6) of T. b. brucei isolated from a dog. Five groups of 5 mice were treated with 0 (control), 0.25, 0.5, 1.0 and 2.0 mg/kg cymelarsan, respectively. The target was to achieve aparasitaemia for 30 days post-treatment, euthanising those that remained parasitaemic or relapsed before then. The 0.25 and 0.5 mg/kg groups remained parasitaemic although the parasitaemic levels were reduced. The 1.0 mg/kg group had a proportion of aparasitaemic mice. However, all mice in the 2.0 mg/kg group remained aparasitaemic until day 20 when 2 mice relapsed. These results suggested that more than 2.0 mg/kg was required to eliminate this strain
显示更多 [+] 显示较少 [-]The distribution of tsetse (Diptera: Glossinidae) and bovine trypanosomosis in the Matutuine district, Maputo Province, Mozambique
2000
Sigauque, I. | Van den Bossche, P. | Moiana, M. | Jamal, S. | Neves, L.
Review of tsetse flies and trypanosomosis in South Africa
1998
Kappmeier, K. | Nevill, E.M. (Agricultural Research Council, Onderstepoort (South Africa). Onderstepoort Veterinary Inst.) | Bagnall, R.J.
The control of Glossina morsitans morsitans (Diptera: Glossinidae) in a settled area in Petauke District (Eastern Province, Zambia) using odour-baited targets
1997
Van den Bossche, P. (Regional Tsetse and Trypanosomosis Control Programme, Harare (Zimbabwe))
Association of trypanosomosis risk with dairy cattle production in western Kenya
2005
Mugunieri, G.L. | Matete, G.O. (Trypanosomosis Research Center, Kikuyu (Kenya))
Evaluation of isometamidium levels in the serum of sheep and goats after prophylactic treatment against trypanosomosis
2004
Wesongah, J.O. | Murilla, G.A. | Kibugu, J.K. (Kenya Trypanosomiasis Research Inst., Kikuyu (Kenya)) | Jones, T.W.
Occurrence of concurrent trypanosomosis, theileriosis, anaplasmosis and helminthosis in Friesian, Zebu and Sahiwal cattle in Uganda
2002
Magona, J.W. | Mayende, J.S.P. (Livestock Health Research Inst., Tororo (Uganda))
A comparative study in the clinical, parasitological and molecular diagnosis of bovine trypanosomosis in Uganda
2003
Magona, J.W. (Glasgow Univ. (United Kingdom). Veterinary School) | Mayende, J.S.P. | Olaho-Mukani, W. | Coleman, P.G. | Jonsson, N.N. | Welburn, S.C. | Eisler, M.C.
Non-immune control of trypanosomosis: In vitro oxidative burst of PMA- and trypanosome-stimulated neutrophils of Boran and N'Dama cattle
2002
Taiwo, V.O. (Ibadan Univ. (Nigeria). Veterinary Pathology Dept.) | Adejinmi, J.O. | Oluwaniyi, J.O.
A review of the infectious diseases of African wild ruminants
2001
Worthington, R.W. | Bigalke, R.D.
