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Genetic changes in pigeon paramyxovirus type-1 induced by serial passages in chickens and microscopic lesions caused by the virus in various avian hosts 全文
2018
Olszewska-Tomczyk Monika | Dolka Izabella | Świętoń Edyta | Śmietanka Krzysztof
Introduction: Genotype VI of avian avulavirus 1 (AAvV-1) has pigeons and doves as its reservoir and is often termed pigeon paramyxovirus type-1 (PPMV-1). The pathogenesis of PPMV-1 infections in poultry is largely obscure. It is known that PPMV-1 requires a series of passages in chickens before it becomes adapted to gallinaceous poultry.
显示更多 [+] 显示较少 [-]Increased p63 expression in canine perianal gland tumours 全文
2018
Kim Soo-Hyeon | Seung Byung-Joon | Cho Seung-Hee | Lim Ha-Young | Park Hee-Myung | Sur Jung-Hyang
p63 is a homologous molecule of p53 and was recently identified as playing important roles in several key cellular processes, including epithelial development and proliferation. Since then, several studies have demonstrated altered p63 expression in various cancers of epithelial origin. Canine perianal gland tumour is one of the most common skin neoplasms in dogs; however, the molecular characteristics of this tumour remain poorly understood. The objective of the present study was to analyse and compare the expression of p63 in canine perianal gland adenomas and carcinomas.
显示更多 [+] 显示较少 [-]Applicability of the protein-lipid profile and activity of lactate dehydrogenase isoenzymes for diagnosing nutritional muscular dystrophy in calves 全文
2018
Żarczyńska Katarzyna | Sobiech Przemysław | Snarska Anna | Tobolski Dawid | Pareek Chandra Shekhar | Bednarek Dariusz
Introduction: In calves, hyposelenosis degenerates skeletal muscles in different parts of the body. The extent of damage to muscle cells can be diagnosed by determining the activity of creatine kinase (CK), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH). The aim of this study was to analyse variations in the serum levels of LDH isoenzymes in calves with nutritional muscular dystrophy (NMD), to determine the applicability of this parameter for diagnosing NMD, and to describe the influence of hyposelenosis on total protein (TP), triglyceride (TG), and cholesterol (CHOL) levels.
显示更多 [+] 显示较少 [-]Influence of the genetic makeup of common carp on the expression of iron-related genes during Trypanoplasma borreli infection 全文
2018
Kamińska-Gibas Teresa | Irnazarow Ilgiz | Szczygieł Joanna | Jurecka Patrycja
Genes related to iron metabolism play an important role in inflammatory response. The objective of this study was to investigate the role of ferritin, transferrin receptors 1a and 1b, and transferrin genes in the response to blood parasite infection in common carp (Cyprinuscarpio L.).
显示更多 [+] 显示较少 [-]Complete genome sequences of three sub-genotype 2.1b isolates of classical swine fever virus in China 全文
2018
Liu Chunxiao | Li Mingliang | Yin Xingwang | Zhang Hongliang | Xiang Lirun | Zhai Hongyue | Wang Congcong | Kan Yunchao | Yao Lunguang | Tian Zhijun | Leng Chaoliang
Classical swine fever (CSF) has caused severe economic losses in pig production in many countries. Recent CSF outbreaks in China are mainly associated with sub-genotype 2.1 of CSF virus (CSFV). Although there is abundant information regarding 2.1 isolates, few data are available on whole-genome analysis.
显示更多 [+] 显示较少 [-]Results of a 16-week safety assurance study with rats fed genetically modified Bt maize: effect on growth and health parameters 全文
2018
Szymczyk Beata | Szczurek Witold | Świątkiewicz Sylwester | Kwiatek Krzysztof | Sieradzki Zbigniew | Mazur Małgorzata | Bednarek Dariusz | Reichert Michał
Introduction: The influence of feeding genetically modified MON 810 hybrid maize on the growth and haematological and biochemical indices of rats was tested.
显示更多 [+] 显示较少 [-]Genotoxicity and mutagenicity of inosine pranobex 全文
2018
Tobólska Sylwia | Terpiłowska Sylwia | Jaroszewski Jerzy | Siwicki Andrzej Krzysztof
Inosine pranobex (Methisoprinol, ISO, Isoprinosine) is an immuno-modulatory antiviral drug that has been licensed since 1971 in several countries worldwide. In humans, the drug is approved for the treatment of viral infections, and it might also have therapeutic use in animals. The aims of the presented work were to investigate the genotoxicity of inosine pranobex on BALB/3T3 clone A1 and HepG2 cell lines and to elucidate its mutagenicity using the Ames test.
显示更多 [+] 显示较少 [-]Fatty acid profile in fat obtained from edible part of land snails harvested in Poland 全文
2018
Szkucik Krzysztof | Ziomek Monika | Paszkiewicz Waldemar | Drozd Łukasz | Gondek Michał | Knysz Przemysław
Introduction: The objective was to determine the content of fatty acids in edible snail fat by snail species, collection site, and processing stage.
显示更多 [+] 显示较少 [-]Effects of repeated lipopolysaccharide treatment on growth performance, immune organ index, and blood parameters of Sprague-Dawley rats 全文
2018
Zhong, Youbao | Zhang, Xianlai | Hu, Xiaofen | Li, Yong
Effects of repeated lipopolysaccharide treatment on growth performance, immune organ index, and blood parameters of Sprague-Dawley rats 全文
2018
Zhong, Youbao | Zhang, Xianlai | Hu, Xiaofen | Li, Yong
The study was designed to investigate the effects of repeated lipopolysaccharide (LPS) treatment on growth performance, lymphoid organ indexes, and blood cells in Sprague-Dawley rats. Forty healthy weaned Sprague-Dawley rats were randomly equally divided into LPS and control groups. Each rat in the LPS group was injected via the caudal vein with LPS (100 μg/kg b.w.) for 10 days, and the control group was treated with an equal volume of normal saline. On the 1ˢᵗ, 4ᵗʰ, 7ᵗʰ, and 10ᵗʰ days, growth performance, lymphoid organ indexes, and blood cells were evaluated in five necropsied rats. When rats were treated 3–10 times with LPS, their body weight and average daily gains increased more slowly than in the control group (P < 0.05). Repeated LPS treatment significantly increased spleen weight and the ratio of spleen to body weight (P < 0.05). White blood cells, neutrophils, and neutrophil percentage increased (P < 0.05) remarkably, but lymphocyte percentage, haemoglobin, and blood platelet counts decreased significantly (P < 0.05). LPS treatment obviously suppresses growth and promotes peripheral immune organ proliferation. It is indicated that host protective mechanism can be activated by multiple small doses of LPS and prevents organs from further damage during stress status.
显示更多 [+] 显示较少 [-]Effects of repeated lipopolysaccharide treatment on growth performance, immune organ index, and blood parameters of Sprague-Dawley rats 全文
2018
Zhong Youbao | Zhang Xianlai | Hu Xiaofen | Li Yong
The study was designed to investigate the effects of repeated lipopolysaccharide (LPS) treatment on growth performance, lymphoid organ indexes, and blood cells in Sprague-Dawley rats.
显示更多 [+] 显示较少 [-]Microbiological quality of farmed grass carp, bighead carp, Siberian sturgeon, and wels catfish from Eastern Poland 全文
2018
Pyz-Łukasik, Renata | Paszkiewicz, Waldemar
Microbiological quality of farmed grass carp, bighead carp, Siberian sturgeon, and wels catfish from Eastern Poland 全文
2018
Pyz-Łukasik, Renata | Paszkiewicz, Waldemar
The purpose of this study was to determine the microbiological quality of food fish and its safety for consumers. The study included 24 fish representing grass carp, bighead carp, Siberian sturgeon, and wels catfish. Specimens were collected in winter. Aerobic bacteria, psychrophilic, Enterobacteriaceae, Staphylococcus spp., and E. coli counts were made, and the presence of Salmonella spp., L. monocytogenes, S. aureus, and other coagulase-positive staphylococci was investigated. The microbiological analysis showed a similar level of aerobic, psychrophilic, and Staphylococcus spp. contamination of the four fish species. The Enterobacteriaceae count was higher in the muscles of grass carp and bighead carp than S. sturgeon and wels catfish. No pathogenic bacteria such as Salmonella spp., E. coli, L. monocytogenes, Staphylococcus aureus, or other coagulase positive staphylococci were found in samples of the examined fish species. The fresh fish examined in this study were of good microbiological quality and there was no health risk for consumers.
显示更多 [+] 显示较少 [-]Microbiological quality of farmed grass carp, bighead carp, Siberian sturgeon, and wels catfish from Eastern Poland 全文
2018
Pyz-Łukasik Renata | Paszkiewicz Waldemar
The purpose of this study was to determine the microbiological quality of food fish and its safety for consumers.
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